Sautereau D, Vire O, Cazes P Y, Cazals J B, Catanzano G, Claude R, Pillegand B
Gastroenterology. 1987 Oct;93(4):715-8. doi: 10.1016/0016-5085(87)90432-x.
This retrospective study was undertaken to evaluate the diagnostic usefulness of 97 sonographically guided fine needle aspiration biopsy cytologies in 92 patients with one or more hepatic lesions suspicious of malignancy. Results of the fine needle aspiration biopsy were then compared with the definitive results obtained by histologic examination, or with the subsequent course of the patient. A final diagnosis of malignancy was established in 65 cases, of which fine needle aspiration biopsy cytology revealed a concordant diagnosis in 54 cases. The diagnostic sensitivity of this technique was 83% for malignant lesions with 93% specificity. Of the 54 cases with malignant cytology, it was possible to distinguish between a primary or secondary lesion in 31 cases (57%). Benign lesions were aspirated in 32 cases, of which 30 cases concorded with the final diagnosis. This study confirms the usefulness of sonographically guided fine needle aspiration biopsy cytology in diagnosing malignant hepatic tumors.
本回顾性研究旨在评估92例有一个或多个可疑恶性肝脏病变患者的97次超声引导下细针穿刺活检细胞学检查的诊断价值。然后将细针穿刺活检结果与组织学检查获得的最终结果或患者的后续病程进行比较。65例确诊为恶性肿瘤，其中细针穿刺活检细胞学检查显示诊断一致的有54例。该技术对恶性病变的诊断敏感性为83%，特异性为93%。在54例恶性细胞学检查病例中，31例（57%）能够区分原发性或继发性病变。32例为良性病变，其中30例与最终诊断一致。本研究证实了超声引导下细针穿刺活检细胞学检查在诊断肝脏恶性肿瘤中的有用性。
