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新冠疫情时代的功能性呼吸评估:肺功能检测实验室的作用

Functional Respiratory Evaluation in the COVID-19 Era: The Role of Pulmonary Function Test Laboratories.

作者信息

Gochicoa-Rangel Laura, Torre-Bouscoulet Luis, Salles Rojas Antonio, Guzmán-Valderrábano Carlos, Silva-Cerón Mónica, Benítez-Pérez Rosaura E, Salas-Escamilla Isabel, Madrid-Mejía Wilmer, Grosso-Espinosa Juan M

机构信息

Department of Respiratory Physiology, Instituto Nacional de Enfermedades Respiratorias "Ismael Cosío Villegas", Mexico City, Mexico.

Laboratory of Pulmonary Function Tests, Instituto de Desarrollo e Innovación en Fisiología Respiratoria, Mexico City, Mexico.

出版信息

Rev Invest Clin. 2020 May 7. doi: 10.24875/RIC.20000250.

DOI:10.24875/RIC.20000250
PMID:33053579
Abstract

The pandemic character of coronavirus disease-19 (COVID-19) requires strategy changes designed to guarantee the safety of patients and health-care professionals. We are greatly concerned by the limitations in the operation of pulmonary function test (PFT) laboratories, since there is a high risk of disease progression in patients with chronic pulmonary diseases, and we are now faced by the influx of a new group of individuals in the recovery phase of post-COVID-19-syndrome that requires evaluation and follow-up of their respiratory function. To reestablish the operation of PFT laboratories limiting the risk of cross-contamination, we herein present the consensus reached by a group of experts in respiratory physiology, most of whom work in PFT laboratories in several Latin American countries, on the applicable recommendations for severe acute respiratory syndrome coronavirus 2 pneumonia survivors when undergoing PFT. We present the safety and hygiene measures that must be adopted in laboratories or centers where PFT is conducted in adults and/or children. These recommendations answer the following questions: which PFT is most recommended in subjects that have recovered from COVID-19; what quality control and safety measures should PFT laboratories implement during this pandemic? And how should we approach non-COVID-19 patients requiring PFT?

摘要

新型冠状病毒肺炎(COVID-19)的大流行特性要求改变策略,以确保患者和医护人员的安全。我们对肺功能测试(PFT)实验室的运行受限深感担忧,因为慢性肺病患者病情进展的风险很高,而且我们现在面临着一批处于COVID-19后综合征康复阶段的新人群,需要对他们的呼吸功能进行评估和随访。为了在限制交叉污染风险的情况下重新开展PFT实验室的工作,我们在此介绍了一组呼吸生理学专家达成的共识,他们中的大多数人在几个拉丁美洲国家的PFT实验室工作,内容是关于严重急性呼吸综合征冠状病毒2肺炎幸存者在进行PFT时的适用建议。我们介绍了在成人和/或儿童进行PFT的实验室或中心必须采取的安全和卫生措施。这些建议回答了以下问题:对于从COVID-19中康复的受试者,最推荐哪种PFT;在此次大流行期间,PFT实验室应实施哪些质量控制和安全措施?以及我们应该如何处理需要进行PFT的非COVID-19患者?

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Small airway dysfunction on impulse oscillometry and pathological signs on lung ultrasound are frequent in post-COVID-19 patients with persistent respiratory symptoms.在新冠病毒感染后持续存在呼吸系统症状的患者中,脉冲震荡肺功能检查的小气道功能障碍和肺部超声的病理征象较为常见。
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