Department of Orthodontics and Dentofacial Orthopedics, School of Dental Medicine, Medical Faculty, University of Bern, Bern, Switzerland.
Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
J Dent Res. 2021 Mar;100(3):245-252. doi: 10.1177/0022034520962751. Epub 2020 Oct 15.
Research waste is highly prevalent across biomedical investigations. We aimed to assess the evidence on the extent of research waste in dental research. We performed a scoping review of empirical evaluations of dental studies assessing the prevalence and impact of limitations in design, conduct, analysis, and reporting of research. PubMed was searched using specific terms to retrieve studies dealing with design, conduct, analysis, and reporting of studies in dentistry, with no year or language restrictions. Of the 1,807 publications identified from the search and from manual searches, 71 were included in this review. The topic and article selection was based on the expert opinion of the authors. The existing evidence suggests that, although there are improvements over time, substantial deficiencies in all areas (design, conduct, analysis, reporting) were prevalent in dental research publications. Waste in research is a multifaceted problem without a simple solution. However, an appreciation of optimal research design and execution is a prerequisite and should be underpinned by policies that include appropriate training in research methods and properly aligned incentives.
研究浪费在生物医学研究中普遍存在。我们旨在评估牙科研究中研究浪费的程度的证据。我们对评估牙科研究中设计、实施、分析和报告方面局限性的普遍性和影响的经验评估进行了范围综述。我们使用特定术语在 PubMed 中进行了检索，以检索涉及牙科研究设计、实施、分析和报告的研究，没有时间或语言限制。从搜索和手动搜索中确定了 1807 篇出版物，其中 71 篇被纳入本综述。主题和文章选择基于作者的专家意见。现有证据表明，尽管随着时间的推移有所改善，但牙科研究出版物在所有领域（设计、实施、分析、报告）都存在严重缺陷。研究中的浪费是一个多方面的问题，没有简单的解决方案。然而，对最佳研究设计和执行的理解是一个前提，应该以包括适当的研究方法培训和适当调整激励措施的政策为基础。
