Department of Gastroenterology and Hepatology, Kusunoki Hospital, Japan.
Department of Gastroenterology and Hepatology, Gunma University Graduate School of Medicine, Japan.
Intern Med. 2021 Mar 15;60(6):873-881. doi: 10.2169/internalmedicine.5891-20. Epub 2020 Oct 14.
Cholangiolocellular carcinoma (CoCC) is a rare primary liver cancer that is difficult diagnose due to a lack of specific imaging findings. We herein report a case of CoCC accompanied by severe alcoholic cirrhosis. Dynamic computed tomography showed a low-density tumor with a faint surrounding enhancement. Gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid-enhanced magnetic resonance imaging revealed iso-intensity in the hepatobiliary phase and a maximum tumor diameter of 53 mm. F-fluoro-2-deoxyglucose position-emission tomography was moderately positive (maximum standardized uptake value: 4.3). CoCC was diagnosed based on the pathological findings, including immunohistochemistry. We discuss the diagnostic imaging findings and review previous reports.
胆管细胞癌(CoCC)是一种罕见的原发性肝癌,由于缺乏特异性影像学表现,诊断较为困难。我们在此报告一例伴有严重酒精性肝硬化的 CoCC 病例。动态计算机断层扫描显示低密度肿瘤,周围轻度增强。钆乙氧基苯甲基-二乙三胺五乙酸增强磁共振成像显示肝胆期等信号,最大肿瘤直径为 53mm。氟-18-氟代脱氧葡萄糖正电子发射断层扫描呈中度阳性(最大标准化摄取值:4.3)。根据包括免疫组织化学在内的病理结果诊断为 CoCC。我们讨论了诊断影像学表现并复习了既往报告。