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成功治疗一例伴有多种影像学表现的低肝功能储备肝内胆小管细胞癌病例报告。

Successfully Treated Case of Cholangiolocellular Carcinoma with a Poor Hepatic Functional Reserve Reporting with Various Imaging Findings.

机构信息

Department of Gastroenterology and Hepatology, Kusunoki Hospital, Japan.

Department of Gastroenterology and Hepatology, Gunma University Graduate School of Medicine, Japan.

出版信息

Intern Med. 2021 Mar 15;60(6):873-881. doi: 10.2169/internalmedicine.5891-20. Epub 2020 Oct 14.

DOI:10.2169/internalmedicine.5891-20
PMID:33055484
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8024949/
Abstract

Cholangiolocellular carcinoma (CoCC) is a rare primary liver cancer that is difficult diagnose due to a lack of specific imaging findings. We herein report a case of CoCC accompanied by severe alcoholic cirrhosis. Dynamic computed tomography showed a low-density tumor with a faint surrounding enhancement. Gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid-enhanced magnetic resonance imaging revealed iso-intensity in the hepatobiliary phase and a maximum tumor diameter of 53 mm. F-fluoro-2-deoxyglucose position-emission tomography was moderately positive (maximum standardized uptake value: 4.3). CoCC was diagnosed based on the pathological findings, including immunohistochemistry. We discuss the diagnostic imaging findings and review previous reports.

摘要

胆管细胞癌（CoCC）是一种罕见的原发性肝癌，由于缺乏特异性影像学表现，诊断较为困难。我们在此报告一例伴有严重酒精性肝硬化的 CoCC 病例。动态计算机断层扫描显示低密度肿瘤，周围轻度增强。钆乙氧基苯甲基-二乙三胺五乙酸增强磁共振成像显示肝胆期等信号，最大肿瘤直径为 53mm。氟-18-氟代脱氧葡萄糖正电子发射断层扫描呈中度阳性（最大标准化摄取值：4.3）。根据包括免疫组织化学在内的病理结果诊断为 CoCC。我们讨论了诊断影像学表现并复习了既往报告。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4d2/8024949/7c7403686678/1349-7235-60-0873-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4d2/8024949/e2da69e94f4c/1349-7235-60-0873-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4d2/8024949/798865e9a866/1349-7235-60-0873-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4d2/8024949/04a6b037fd45/1349-7235-60-0873-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4d2/8024949/b8be8f4568ed/1349-7235-60-0873-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4d2/8024949/64573ed9543b/1349-7235-60-0873-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4d2/8024949/b1508b680686/1349-7235-60-0873-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4d2/8024949/7c7403686678/1349-7235-60-0873-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4d2/8024949/e2da69e94f4c/1349-7235-60-0873-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4d2/8024949/798865e9a866/1349-7235-60-0873-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4d2/8024949/04a6b037fd45/1349-7235-60-0873-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4d2/8024949/b8be8f4568ed/1349-7235-60-0873-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4d2/8024949/64573ed9543b/1349-7235-60-0873-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4d2/8024949/b1508b680686/1349-7235-60-0873-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4d2/8024949/7c7403686678/1349-7235-60-0873-g007.jpg

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Successful local treatment for repeated hepatic recurrences of cholangiolocellular carcinoma: a report on a long-term survivor.肝内胆管细胞癌反复肝复发的成功局部治疗：一例长期存活者的报告
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Cholangiolocellular Carcinoma in a Young Patient Who Showed Sustained Virological Response after Treatment for Hepatitis C Virus Infection.
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