黏膜免疫：母乳的免疫学
Mucosal immunity: the immunology of breast milk.
作者信息
Slade H B, Schwartz S A
出版信息
J Allergy Clin Immunol. 1987 Sep;80(3 Pt 1):348-58. doi: 10.1016/0091-6749(87)90041-8.
Abstract
The mammary glands represent one part of the mucosal immune system, a definable, subunit of humoral and cellular immune functions in man that appears to have developed particular qualities well suited to guard our interface with the environment. As our understanding of secretory immunoglobulins and lymphocyte migration patterns continues to develop, the immunologic components found in breast milk appear increasingly likely to play a specific immunologic role in the protection of the nursing infant. The biologic basis for the observed protective effect of breast-feeding is reviewed with an emphasis on the mechanisms involved in the development and maintenance of mucosal immunity in general.
摘要
乳腺是黏膜免疫系统的一部分，黏膜免疫系统是人体体液免疫和细胞免疫功能中一个可明确界定的亚单位，它似乎具备了一些特别的特性，非常适合守护我们与外界环境的界面。随着我们对分泌型免疫球蛋白和淋巴细胞迁移模式的理解不断深入，母乳中发现的免疫成分在保护哺乳婴儿方面发挥特定免疫作用的可能性似乎越来越大。本文综述了母乳喂养所观察到的保护作用的生物学基础，重点是一般黏膜免疫的发育和维持所涉及的机制。
相似文献
1
Mucosal immunity: the immunology of breast milk.黏膜免疫：母乳的免疫学
J Allergy Clin Immunol. 1987 Sep;80(3 Pt 1):348-58. doi: 10.1016/0091-6749(87)90041-8.
2
The mucosal immune system and its integration with the mammary glands.黏膜免疫系统及其与乳腺的整合。
J Pediatr. 2010 Feb;156(2 Suppl):S8-15. doi: 10.1016/j.jpeds.2009.11.014.
3
Mucosal immunity of the mammary gland and immunology of mother/newborn interrelation.乳腺的黏膜免疫与母婴关系免疫学。
Arch Immunol Ther Exp (Warsz). 1990;38(1-2):145-64.
4
Maternal-neonatal interactions and human breast milk.母婴互动与母乳
Prog Clin Biol Res. 1981;70:171-82.
5
Immunologic aspects of breast feeding, antiinfectious activity of breast milk.母乳喂养的免疫学方面，母乳的抗感染活性。
Semin Perinatol. 1979 Jul;3(3):255-70.
6
Human milk: Defense against infection.母乳：抵御感染。
Prog Clin Biol Res. 1981;61:147-59.
7
Mucosal immunity--from past to present.
Monogr Allergy. 1988;24:1-8.
8
Antibodies in milk.
J Reprod Fertil. 1982 Jul;65(2):537-43. doi: 10.1530/jrf.0.0650537.
9
Breast feeding and the intestinal microflora of the infant--implications for protection against infectious diseases.母乳喂养与婴儿肠道微生物群——对预防传染病的意义。
Adv Exp Med Biol. 2000;478:77-93. doi: 10.1007/0-306-46830-1_7.
10
The immune response of the mammary gland and its significance for the neonate.乳腺的免疫反应及其对新生儿的意义。
Ann Allergy. 1984 Dec;53(6 Pt 2):576-82.
引用本文的文献
1
Glycerol Monolaurate Contributes to the Antimicrobial and Anti-inflammatory Activity of Human Milk.甘油单月桂酸酯有助于人乳的抗菌和抗炎活性。
Sci Rep. 2019 Oct 10;9(1):14550. doi: 10.1038/s41598-019-51130-y.
2
An Infant Mouse Model of Influenza Virus Transmission Demonstrates the Role of Virus-Specific Shedding, Humoral Immunity, and Sialidase Expression by Colonizing Streptococcus pneumoniae.流感病毒传播的婴儿鼠模型显示定植肺炎链球菌的病毒特异性脱落、体液免疫和神经氨酸酶表达的作用。
mBio. 2018 Dec 18;9(6):e02359-18. doi: 10.1128/mBio.02359-18.
3
The best of intentions: Prenatal breastfeeding intentions and infant health.最美好的意愿：产前母乳喂养意愿与婴儿健康
SSM Popul Health. 2018 Jun 18;5:86-100. doi: 10.1016/j.ssmph.2018.05.002. eCollection 2018 Aug.
4
Comparing the Impact of Topical Application of Human Milk and Chlorhexidine on Cord Separation Time in Newborns.比较人乳局部应用与洗必泰对新生儿脐带脱落时间的影响。
Pak J Med Sci. 2016 Jan-Feb;32(1):239-43. doi: 10.12669/pjms.321.8223.
5
Immune cell-mediated protection of the mammary gland and the infant during breastfeeding.母乳喂养期间免疫细胞对乳腺和婴儿的保护作用。
Adv Nutr. 2015 May 15;6(3):267-75. doi: 10.3945/an.114.007377. Print 2015 May.
6
Maternal and infant infections stimulate a rapid leukocyte response in breastmilk.产妇和婴儿感染会刺激母乳中白细胞的快速反应。
Clin Transl Immunology. 2013 Apr 12;2(4):e3. doi: 10.1038/cti.2013.1. eCollection 2013 Apr.
7
Aetiology and clinical features of dysentery in children aged <5 years in rural Bangladesh.孟加拉国农村地区<5 岁儿童痢疾的病因和临床特征。
Epidemiol Infect. 2014 Jan;142(1):90-8. doi: 10.1017/S0950268813000666. Epub 2013 Apr 8.
8
DHA supplementation during pregnancy and lactation affects infants' cellular but not humoral immune response.孕期和哺乳期补充 DHA 会影响婴儿的细胞免疫反应，但不会影响体液免疫反应。
Mediators Inflamm. 2011;2011:493925. doi: 10.1155/2011/493925. Epub 2011 Sep 18.
9
Comparison of concentration and avidity of specific antibodies to E. coli in breast milk and serum.母乳和血清中抗大肠杆菌特异性抗体的浓度及亲和力比较。
Immunology. 1989 Mar;66(3):394-7.
10
Evidence for long-term memory of the mucosal immune system: milk secretory immunoglobulin A against Shigella lipopolysaccharides.黏膜免疫系统长期记忆的证据：针对志贺氏菌脂多糖的乳汁分泌型免疫球蛋白A
J Clin Microbiol. 1991 Nov;29(11):2599-603. doi: 10.1128/jcm.29.11.2599-2603.1991.
本文引用的文献
1
Fc receptor-mediated transport of immunoglobulin across the intestinal epithelium of the neonatal rodent.Fc受体介导的免疫球蛋白跨新生啮齿动物肠上皮的转运
Immunol Today. 1984 Dec;5(12):364-6. doi: 10.1016/0167-5699(84)90080-X.
2
Does breast-feeding prevent the development of allergy?
Immunol Today. 1983 Aug;4(8):215-7. doi: 10.1016/0167-5699(83)90029-4.
3
CHARACTERISTICS OF AN IMMUNE SYSTEM COMMON TO CERTAIN EXTERNAL SECRETIONS.某些外分泌液共有的免疫系统特征。
J Exp Med. 1965 Jan 1;121(1):101-24. doi: 10.1084/jem.121.1.101.
4
Comparative immunological studies of the immune globulins of human milk and of blood serum.人乳与血清免疫球蛋白的比较免疫学研究。
Int Arch Allergy Appl Immunol. 1961;18:241-67. doi: 10.1159/000229177.
5
Dimeric IgA in the rat is transferred from serum into bile but not into milk.大鼠体内的二聚体免疫球蛋白A（IgA）从血清转移至胆汁，但不会转移至乳汁。
Scand J Immunol. 1981 Jul;14(1):95-8. doi: 10.1111/j.1365-3083.1981.tb00188.x.
6
7
Secretory IgA antibodies synergize with IgG in promoting ADCC by human polymorphonuclear cells, monocytes, and lymphocytes.分泌型IgA抗体与人多形核细胞、单核细胞及淋巴细胞协同作用，促进抗体依赖的细胞介导的细胞毒性作用（ADCC）。
Cell Immunol. 1981 Mar 15;59(1):75-81. doi: 10.1016/0008-8749(81)90435-4.
8
Antibody content of rabbit milk and serum following inhalation or ingestion of respiratory syncytial virus and bovine serum albumin.吸入或摄入呼吸道合胞病毒和牛血清白蛋白后兔奶和血清中的抗体含量。
Clin Exp Immunol. 1982 Apr;48(1):91-101.
9
IgA subclasses in various secretions and in serum.各种分泌物及血清中的IgA亚类。
Immunology. 1982 Oct;47(2):383-5.
10
Breast-feeding and infant health in a rural US community.
Am J Dis Child. 1982 Jan;136(1):36-8. doi: 10.1001/archpedi.1982.03970370038009.
Zotero 插件