Slade H B, Schwartz S A
J Allergy Clin Immunol. 1987 Sep;80(3 Pt 1):348-58. doi: 10.1016/0091-6749(87)90041-8.
The mammary glands represent one part of the mucosal immune system, a definable, subunit of humoral and cellular immune functions in man that appears to have developed particular qualities well suited to guard our interface with the environment. As our understanding of secretory immunoglobulins and lymphocyte migration patterns continues to develop, the immunologic components found in breast milk appear increasingly likely to play a specific immunologic role in the protection of the nursing infant. The biologic basis for the observed protective effect of breast-feeding is reviewed with an emphasis on the mechanisms involved in the development and maintenance of mucosal immunity in general.
乳腺是黏膜免疫系统的一部分，黏膜免疫系统是人体体液免疫和细胞免疫功能中一个可明确界定的亚单位，它似乎具备了一些特别的特性，非常适合守护我们与外界环境的界面。随着我们对分泌型免疫球蛋白和淋巴细胞迁移模式的理解不断深入，母乳中发现的免疫成分在保护哺乳婴儿方面发挥特定免疫作用的可能性似乎越来越大。本文综述了母乳喂养所观察到的保护作用的生物学基础，重点是一般黏膜免疫的发育和维持所涉及的机制。
