Department of Psychiatry, Nepean Hospital, Penrith, NSW, Australia.
Nepean Clinical School, Sydney Medical School, Faculty of Medicine and Health, University of Sydney, Penrith, NSW, Australia.
Aust N Z J Psychiatry. 2020 Dec;54(12):1173-1181. doi: 10.1177/0004867420963743. Epub 2020 Oct 16.
There is a growing realisation that anxiety symptoms and disorders during pregnancy are associated with various negative outcomes. The aims of this study were to identify latent classes of anxiety symptom trajectories during pregnancy, compare anxiety levels between pregnancy trimesters and ascertain the predictors of anxiety symptom trajectories.
Two hundred pregnant women in their first trimester who attended obstetric clinics at the local hospital were recruited. Three self-report questionnaires assessing anxiety levels were administered at three time points during pregnancy. Latent class growth analysis was used to identify anxiety symptom trajectories, and logistic regression analysis was performed to ascertain the predictors of latent class membership.
Data for analyses were available for 188 women. Two anxiety symptom trajectories were identified: a 'high-anxiety' trajectory (13.3% of participating women) and 'low-anxiety' trajectory (86.7%). This finding was consistent across all the anxiety measures used in the study. Overall, anxiety levels gradually decreased during pregnancy, with a significant decrease between the first and second trimesters on some measures. Past mental disorders and significant stressors in the preceding 6 months predicted membership in the 'high-anxiety' trajectory group.
These findings support an early assessment of anxiety in pregnant women. If untreated, a high level of anxiety in the first trimester is likely to persist throughout pregnancy, although it may decrease somewhat. An early recognition of pathological anxiety during pregnancy allows its timely treatment and prevention of unfavourable outcomes.
越来越多的人意识到,孕期的焦虑症状和障碍与各种不良后果有关。本研究的目的是确定孕期焦虑症状轨迹的潜在类别,比较孕期各 trimester 的焦虑水平,并确定焦虑症状轨迹的预测因素。
招募了 200 名在当地医院妇产科诊所就诊的孕早期妇女。在孕期的三个时间点,使用三个自我报告问卷评估焦虑水平。使用潜在类别增长分析来识别焦虑症状轨迹,并进行逻辑回归分析以确定潜在类别成员的预测因素。
可用于分析的数据为 188 名妇女。确定了两种焦虑症状轨迹:“高焦虑”轨迹(13.3%的参与妇女)和“低焦虑”轨迹(86.7%)。这一发现与研究中使用的所有焦虑测量方法一致。总体而言,孕期焦虑水平逐渐下降,一些测量指标在第一和第二 trimester 之间显著下降。过去的精神障碍和前 6 个月的重大压力源预测了“高焦虑”轨迹组的成员资格。
这些发现支持对孕妇进行早期焦虑评估。如果未经治疗,第一 trimester 高水平的焦虑可能会持续整个孕期,尽管可能会有所下降。早期识别孕期病理性焦虑可及时进行治疗,预防不良结局。