Zimmermann Martha, Mahanna Allexis, Shashkova Elizabeth, Drouhard Rebecca, Carr Catherine, Sheldrick R Christopher, Boudreaux Edwin D, Schmidt Norman B, Byatt Nancy
UMass Chan Medical School, 55 N Lake Ave, Worcester, MA 01655, USA.
UMass Memorial Health, 55 N Lake Ave, Worcester, MA 01655, USA.
Ment Health Prev. 2025 Mar;37. doi: 10.1016/j.mhp.2025.200397. Epub 2025 Jan 14.
Anxiety Sensitivity (AS), the trait-like tendency to interpret anxiety-related sensations as harmful, is a well-established risk factor for anxiety disorders and other mental health conditions. Less is known about the role of AS in perinatal mental health-encompassing pregnancy and the postpartum period-despite the heightened risk for anxiety and anxiety-related disorders such as Obsessive Compulsive Disorder and Posttraumatic Stress Disorder (PTSD).
The goal of this scoping review was to examine 1) the state of research on AS in perinatal populations, 2) its relationship with mental health and pregnancy-specific outcomes, and 3) its integration into clinical interventions.
We conducted a systematic literature search using PubMed, Scopus, PsycInfo, CINAHL. Study inclusion criteria were: 1) participants were pregnant or <1 year postpartum, and 2) AS was assessed.
Twenty studies met inclusion criteria. Most studies examined cross-sectional or prospective relationships between AS and mental health and related outcomes, finding positive association between AS and PTSD symptoms, depression symptoms, anxiety symptoms, fetal health anxiety, pregnancy-related anxiety, and fear of childbirth. Results were more mixed for aspects of pain during labor (e.g., anesthetic consumption). Two Randomized Clinical Trials and two case studies included AS as an outcome measure.
This review extends previous findings in the general population by highlighting associations between AS and perinatal mental health. Future research should expand the breadth scope of outcomes assessed and investigate AS as a modifiable target in interventions to enhance perinatal mental health outcomes.
焦虑敏感性(AS)是一种将与焦虑相关的感觉解释为有害的特质性倾向,是焦虑症和其他心理健康状况公认的风险因素。尽管孕期和产后患焦虑症及强迫症和创伤后应激障碍(PTSD)等焦虑相关障碍的风险增加,但关于AS在围产期心理健康(包括孕期和产后)中的作用却知之甚少。
本综述的目的是研究1)围产期人群中AS的研究现状,2)其与心理健康和特定妊娠结局的关系,3)其在临床干预中的整合情况。
我们使用PubMed、Scopus、PsycInfo、CINAHL进行了系统的文献检索。研究纳入标准为:1)参与者为孕妇或产后<1年,2)评估了AS。
20项研究符合纳入标准。大多数研究考察了AS与心理健康及相关结局之间的横断面或前瞻性关系,发现AS与PTSD症状、抑郁症状、焦虑症状、胎儿健康焦虑、妊娠相关焦虑和分娩恐惧之间存在正相关。关于分娩时疼痛方面(如麻醉药物使用)的结果则更为复杂。两项随机临床试验和两项案例研究将AS作为结局指标。
本综述通过强调AS与围产期心理健康之间的关联,扩展了以往在普通人群中的研究结果。未来的研究应扩大评估结局的广度,并将AS作为改善围产期心理健康结局干预措施中的一个可改变目标进行研究。