左心发育不全综合征的诺伍德手术结果。
Outcome of Norwood operation for hypoplastic left heart syndrome.
作者信息
Rai Vivek, Mroczek Tomasz, Szypulski Aleksander, Pac Agnieszka, Gładki Marcin, Dudyńska Mirosława, Skalski Janusz
机构信息
Department of Pediatric Cardiac Surgery, Jagiellonian University Children's Hospital, Krakow, Poland.
Department of Epidemiology and Public Health, Jagiellonian University, Krakow, Poland.
出版信息
Indian J Thorac Cardiovasc Surg. 2018 Jul;34(3):337-344. doi: 10.1007/s12055-017-0603-1. Epub 2017 Nov 22.
PURPOSE
The Norwood procedure, the first surgical step of staged palliation for hypoplastic left heart syndrome (HLHS), is also applied for other complex single ventricle lesions. This study aimed to evaluate the outcome of the Norwood operation in a single center over 4 years and to identify clinical and anatomic risk factors for overall mortality.
METHODS
A retrospective review of the pediatric cardiovascular surgery database was performed to identify infants with HLHS who underwent NP (Norwood procedure) at our institution between January 2007 and December 2011. Our study population consisted of 85 patients with HLHS.
RESULTS
Early mortality (30 days postoperative period) between January 2007 and December 2011 for Norwood operation was 7 (8.2%) out of 85 patient, and overall mortality was 24 (28.2%).
CONCLUSION
Our single-center experience shows that the Norwood operation can be performed for complex single ventricle lesions with similarly good early outcomes regardless of the underlying anatomy.
目的
诺伍德手术是左心发育不全综合征（HLHS）分期姑息治疗的第一步手术，也适用于其他复杂单心室病变。本研究旨在评估单中心4年间诺伍德手术的结果，并确定总体死亡率的临床和解剖学危险因素。
方法
对儿科心血管外科数据库进行回顾性分析，以确定2007年1月至2011年12月期间在本机构接受诺伍德手术（NP）的HLHS婴儿。我们的研究人群包括85例HLHS患者。
结果
2007年1月至2011年12月期间，85例接受诺伍德手术的患者中，早期死亡率（术后30天）为7例（8.2%），总体死亡率为24例（28.2%）。
结论
我们的单中心经验表明，无论潜在解剖结构如何，诺伍德手术均可用于复杂单心室病变，且早期效果相似。
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