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The Role of Endothelial Cells in the Onset, Development and Modulation of Vein Graft Disease.内皮细胞在静脉移植物疾病的发生、发展和调节中的作用。
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Effects of the P-Selectin Antagonist Inclacumab on Myocardial Damage After Percutaneous Coronary Intervention According to Timing of Infusion: Insights From the SELECT-ACS Trial.依输注时机而定的 P 选择素拮抗剂依替巴肽对经皮冠状动脉介入治疗后心肌损伤的影响：来自 SELECT-ACS 试验的观察。
J Am Heart Assoc. 2016 Nov 16;5(11):e004255. doi: 10.1161/JAHA.116.004255.
2
Traditional graft preparation decreases physiologic responses, diminishes viscoelasticity, and reduces cellular viability of the conduit: A porcine saphenous vein model.传统的移植物制备会降低生理反应、减弱粘弹性并降低管道的细胞活力：猪隐静脉模型。
Vasc Med. 2016 Oct;21(5):413-421. doi: 10.1177/1358863X16649040. Epub 2016 May 23.
3
Vein graft failure: from pathophysiology to clinical outcomes.静脉移植物失败：从病理生理学到临床结局。
Nat Rev Cardiol. 2016 Aug;13(8):451-70. doi: 10.1038/nrcardio.2016.76. Epub 2016 May 19.
4
Trends in Patient Characteristics and Outcomes of Coronary Artery Bypass Grafting in the 2000 to 2012 Medicare Population.2000年至2012年医疗保险人群冠状动脉旁路移植术的患者特征及结局趋势
Ann Thorac Surg. 2016 Jul;102(1):132-8. doi: 10.1016/j.athoracsur.2016.01.016. Epub 2016 Mar 2.
5
Preservation of Endothelial and Smooth Muscle Function of Human Saphenous Vein Transplants.人隐静脉移植血管内皮及平滑肌功能的保留
Exp Clin Transplant. 2016 Feb;14(1):86-92.
6
TiProtec preserves endothelial function in a rat model.TiProtec在大鼠模型中可维持内皮功能。
J Surg Res. 2016 Jan;200(1):346-55. doi: 10.1016/j.jss.2015.06.062. Epub 2015 Jul 2.
7
The Preservation and Handling of Vein Grafts in Current Surgical Practice: Findings of a Survey Among Cardiovascular Surgeons of Top-Ranked US Hospitals.当前外科手术中静脉移植物的保存与处理：美国顶级医院心血管外科医生的调查结果
JAMA Surg. 2015 Jul;150(7):681-3. doi: 10.1001/jamasurg.2015.0404.
8
A Randomized Trial of External Stenting for Saphenous Vein Grafts in Coronary Artery Bypass Grafting.冠状动脉旁路移植术中隐静脉移植物外部支架置入的随机试验
Ann Thorac Surg. 2015 Jun;99(6):2039-45. doi: 10.1016/j.athoracsur.2015.01.060. Epub 2015 Apr 15.
9
Vein graft preservation solutions, patency, and outcomes after coronary artery bypass graft surgery: follow-up from the PREVENT IV randomized clinical trial.静脉移植物保存液、冠状动脉旁路移植术后通畅率和结局：来自预防性静脉内 IV 随机临床试验的随访。
JAMA Surg. 2014 Aug;149(8):798-805. doi: 10.1001/jamasurg.2014.87.
10
A randomized comparison of the Saphenous Vein Versus Right Internal Thoracic Artery as a Y-Composite Graft (SAVE RITA) trial: One-year angiographic results and mid-term clinical outcomes.大隐静脉与右胸廓内动脉作为Y形复合移植物的随机对照试验（SAVE RITA）：1年血管造影结果及中期临床结局
J Thorac Cardiovasc Surg. 2014 Sep;148(3):901-7; discussion 907-8. doi: 10.1016/j.jtcvs.2014.03.057. Epub 2014 May 16.

储存溶液对内皮功能和大隐静脉移植物通畅性的影响。

The effect of storage solutions on endothelial function and saphenous vein graft patency.

作者信息

Bouhout Ismail, Ali Walid Ben, Perrault Louis Paul

机构信息

Department of Cardiovascular Surgery, Montreal Heart Institute, 5000 Belanger Street, Montreal, QC H1T 1C8 Canada.

出版信息

Indian J Thorac Cardiovasc Surg. 2018 Dec;34(Suppl 3):258-265. doi: 10.1007/s12055-018-0720-5. Epub 2018 Sep 20.

DOI:10.1007/s12055-018-0720-5
PMID:33060947
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7525915/
Abstract

Vein graft failure is a complex mechanism that can be triggered immediately after surgical harvesting. Storage solutions have a major role in preventing endothelial cell damage during harvesting. While normal saline is still widely used, buffered solutions seem to better preserve endothelial integrity and function. This review aims to summarize the current literature surrounding vein graft storage solutions.

摘要

静脉移植物失败是一种复杂的机制，可在手术获取后立即引发。储存溶液在防止获取过程中内皮细胞损伤方面起着主要作用。虽然生理盐水仍被广泛使用，但缓冲溶液似乎能更好地保持内皮完整性和功能。本综述旨在总结当前围绕静脉移植物储存溶液的文献。