Graulus Eric, Schepens Marc
Department of Cardiovascular Surgery, General Hospital Saint John, Ruddershove 10, B-8000 Bruges, Belgium.
Indian J Thorac Cardiovasc Surg. 2019 Jun;35(Suppl 2):186-191. doi: 10.1007/s12055-018-0664-9. Epub 2018 Apr 14.
Thoracic aortic graft infections are infrequent, but are associated with high mortality and morbidity risk. To prevent these life-threatening infections, one must be aware of pathogenesis. When it occurs, a multidisciplinary (surgeon, radiologist, microbiologist, nuclear specialist, infectiologist, anesthesiologist, intensive care specialist) cascade must be initiated. A fast and accurate diagnosis using diagnostic criteria is vital. The appropriate treatment consists of a combination of antibiotics and surgery. Whether or not the vascular prosthesis is preserved depends on a case-by-case basis (tailor-made). Several graft preservation strategies have proven their effectiveness.
胸主动脉移植物感染并不常见,但与高死亡率和高发病风险相关。为预防这些危及生命的感染,必须了解其发病机制。感染发生时,必须启动多学科(外科医生、放射科医生、微生物学家、核医学专家、感染病学家、麻醉医生、重症监护专家)联合诊疗流程。使用诊断标准进行快速准确的诊断至关重要。恰当的治疗包括抗生素治疗与手术相结合。血管假体是否保留需依具体情况而定(量身定制)。几种移植物保留策略已证明其有效性。