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健康个体中的口腔定植:患病率、基因型多样性、随时间的稳定性及传播性。

Oral colonization in healthy individuals: prevalence, genotypic diversity, stability along time and transmissibility.

作者信息

Gerós-Mesquita Ângela, Carvalho-Pereira Joana, Franco-Duarte Ricardo, Alves Armandino, Gerós Hernâni, Pais Célia, Sampaio Paula

机构信息

CBMA (Centre of Molecular and Environmental Biology) / Department of Biology / University of Minho, Braga, Portugal.

Centro De Ortodontia De Braga, Braga, Portugal.

出版信息

J Oral Microbiol. 2020 Sep 14;12(1):1820292. doi: 10.1080/20002297.2020.1820292.

DOI:10.1080/20002297.2020.1820292
PMID:33062200
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7534343/
Abstract

In this study, 181 healthy individuals, including 29 couples, were analysed regarding oral yeast colonization using a culture-based approach. Results showed that 39% of the individuals were yeast carriers, 89% being colonized with , 5% with , 3% with and 3% with . Sixty-two percent of the couples had at least one member colonized. Colonization and CFU counts were higher in the couples´ group. Eighty percent of the volunteers were colonized with strains with only one CAI genotype, while two but similar CAI genotypes inhabited the oral cavity of the remaining 20% individuals. The same CAI genotypes were found in 66.6% of the couples when both were colonized. Our results indicate that the intimacy among couples increases the probability of heavy cross-colonization, which is potentiated when one member of the couple is a smoker.

摘要

在本研究中,采用基于培养的方法对181名健康个体(包括29对夫妇)进行了口腔酵母菌定植分析。结果显示,39%的个体为酵母菌携带者,89%的个体定植有 ,5%的个体定植有 ,3%的个体定植有 ,3%的个体定植有 。62%的夫妇中至少有一名成员被定植。夫妇组的定植率和菌落形成单位计数更高。80%的志愿者定植有仅一种CAI基因型的 菌株,而其余20%个体的口腔中存在两种但相似的CAI基因型。当夫妇双方都被定植时,66.6%的夫妇中发现了相同的CAI基因型。我们的结果表明,夫妻间的亲密关系增加了严重交叉定植的可能性,当夫妻中的一方为吸烟者时这种可能性会增强。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21a8/7534343/811bdc76966e/ZJOM_A_1820292_F0003_B.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21a8/7534343/06e70a0826d2/ZJOM_A_1820292_F0001_B.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21a8/7534343/45af48faf842/ZJOM_A_1820292_F0002_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21a8/7534343/811bdc76966e/ZJOM_A_1820292_F0003_B.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21a8/7534343/06e70a0826d2/ZJOM_A_1820292_F0001_B.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21a8/7534343/45af48faf842/ZJOM_A_1820292_F0002_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21a8/7534343/811bdc76966e/ZJOM_A_1820292_F0003_B.jpg

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