Arroyo Murillo Gabriela A, Choppin De Janvry Eleonore, Garofalo Manuela, Della Pietra Fatima
General Surgery and Organ Transplantation Unit, Department of Surgery, University of Rome La Sapienza, Rome, Italy.
General Surgery and Bariatric Surgery Unit, Department of Surgery, Civita Castellana Hospital, Civita Castellana, Italy.
Case Rep Surg. 2020 Sep 29;2020:8879609. doi: 10.1155/2020/8879609. eCollection 2020.
Primary ampullary neoplasms have origin in the ampulla of Vater, an anatomical structure where the common bile duct and the pancreatic duct join together as a common channel. It represents <0.5% of all gastrointestinal cancers and approximately 7% of all periampullary cancers. The adenocarcinomas arising in this region originate from different epithelial cellular constituents present at the site, the histopathological classification encompass: intestinal type, pancreaticobiliary type, and mixed type. Pancreaticoduodenectomy is the treatment of choice when there is an overt or highly suspicious malignant behaviour. We present here the case of a 74-year-old male patient who presented to our department for further investigation of obstructive jaundice and a pancreatic mass associated with a six-month history of significant weight loss and mild epigastric pain. Eventually, a total splenopancreatectomy was performed given the extension of structural anomalies of the organ secondary to an ampullary adenocarcinoma.
原发性壶腹肿瘤起源于 Vater 壶腹，这是一种解剖结构，胆总管和胰管在此处汇合成一条共同通道。它占所有胃肠道癌症的比例不到 0.5%，约占所有壶腹周围癌的 7%。该区域发生的腺癌起源于该部位存在的不同上皮细胞成分，组织病理学分类包括：肠型、胰胆管型和混合型。当存在明显或高度可疑的恶性行为时，胰十二指肠切除术是首选治疗方法。我们在此介绍一名 74 岁男性患者的病例，该患者因阻塞性黄疸和胰腺肿块前来我院进一步检查，伴有六个月的显著体重减轻和轻度上腹部疼痛病史。最终，鉴于继发于壶腹腺癌的器官结构异常范围，实施了全胰脾切除术。
