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单节段与双节段经皮椎体后凸成形术治疗后壁破裂骨质疏松性椎体压缩骨折的短期疗效比较

[Short-term effectiveness comparison of unipedicular versus bipedicular percutaneous kyphoplasty for osteoporotic vertebral compression fractures with posterior wall broken].

作者信息

Gou Yongsheng, Li Haibo, Fu Bolin, Che Zheng

机构信息

Department of Orthopaedics, the First People's Hospital of Shuangliu District, Chengdu Sichuan, 610200, P.R.China.

出版信息

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2020 Oct 15;34(10):1281-1287. doi: 10.7507/1002-1892.201907001.

DOI:10.7507/1002-1892.201907001
PMID:33063494
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8171888/
Abstract

OBJECTIVE

To compare the short-term effectiveness and safety of unipedicular versus bipedicular percutaneous kyphoplasty (PKP) for osteoporotic vertebral compression fracture (OVCF) with posterior wall broken.

METHODS

The clinical data of 68 patients with OVCF with posterior wall broken and without posterior ligament complex injury and spinal cord nerve injury between June 2013 and December 2018 were retrospectively analyzed. According to the different operative approaches, the patients were divided into two groups: group A (36 cases received PKP via bilateral pedicle puncture) and group B (32 cases received PKP via unilateral pedicle paracentesis). There was no significant difference between the two groups in gender, age, fracture vertebra distribution, time from injury to operation, preoperative pain visual analogue scale (VAS) score, Oswestry disability index (ODI), and height of injured vertebra ( >0.05). The operation time, intraoperative fluoroscopy times, and bone cement volume were recorded and compared between the two groups. The VAS score and ODI score were used to evaluate the effectiveness before operation, at 1 day and 6 months after operation; the height of injured vertebra was measured on the lateral X-ray film, and the recovery height of injured vertebra at 1 day after operation and the loss height of injured vertebra at 6 months after operation were calculated; the intraoperative and postoperative complications of the two groups were recorded.

RESULTS

The operation time, intraoperative fluoroscopy times, and bone cement volume of group B were significantly less than those of group A ( <0.05). All patients were followed up 10-35 months, with an average of 18 months. During the operation, there were 2 cases (5.56%) of cement leakage in group A and 9 cases (28.13%) in group B, showing significant difference ( =4.808, =0.028). There was no adverse reactions of bone cement, iatrogenic spinal cord injury, infection of puncture port, or other complications in the two groups. During the follow-up period, there were 3 cases (8.3%) of adjacent vertebral fractures in group A and 2 cases (6.3%) in group B, showing no significant difference between the two groups ( =0.027, =0.869). The height of injured vertebra of the two groups at 1 day and 6 months after operation were significantly improved when compared with preoperative ones ( <0.05). There was no significant difference in the height of injured vertebrae and the recovery height of injured vertebra at 1 day after operation between the two groups ( >0.05). However, at 6 months after operation, the height of injured vertebra in group B was significantly lower than that in group A ( <0.05), and the loss height of injured vertebra in group B was significantly higher than that in group A ( <0.05). The VAS score and ODI score at 1 day and 6 months after operation were significantly improved when compared with preoperative ones in both groups ( <0.05), but there was no significant difference between the two groups ( >0.05).

CONCLUSION

Both bipedicular and unipedicular PKP can obtain satisfactory effectiveness for the treatment of OVCF with posterior wall broken, but the former may have advantages of lower cement leakage rate and less height loss.

摘要

目的

比较单节段与双节段经皮椎体后凸成形术(PKP)治疗后壁破裂的骨质疏松性椎体压缩骨折(OVCF)的短期疗效及安全性。

方法

回顾性分析2013年6月至2018年12月期间68例后壁破裂且无后纵韧带复合体损伤及脊髓神经损伤的OVCF患者的临床资料。根据手术入路不同,将患者分为两组:A组(36例采用双侧椎弓根穿刺行PKP)和B组(32例采用单侧椎弓根旁穿刺行PKP)。两组患者在性别、年龄、骨折椎体分布、受伤至手术时间、术前疼痛视觉模拟评分(VAS)、Oswestry功能障碍指数(ODI)及伤椎高度方面比较,差异均无统计学意义(>0.05)。记录并比较两组患者的手术时间、术中透视次数及骨水泥用量。采用VAS评分和ODI评分评估术前、术后1天及术后6个月的疗效;在侧位X线片上测量伤椎高度,计算术后1天伤椎恢复高度及术后6个月伤椎丢失高度;记录两组患者术中及术后并发症。

结果

B组患者的手术时间、术中透视次数及骨水泥用量均明显少于A组(<0.05)。所有患者均获随访10~35个月,平均18个月。术中,A组有2例(5.56%)发生骨水泥渗漏,B组有9例(28.13%)发生骨水泥渗漏,差异有统计学意义(=4.808,=0.028)。两组均未发生骨水泥不良反应、医源性脊髓损伤、穿刺口感染及其他并发症。随访期间,A组有3例(8.3%)发生相邻椎体骨折,B组有2例(6.3%)发生相邻椎体骨折,两组比较差异无统计学意义(=0.027,=0.869)。两组术后1天及术后6个月伤椎高度均较术前明显改善(<0.05)。两组术后1天伤椎高度及伤椎恢复高度比较,差异无统计学意义(>0.05)。但术后6个月,B组伤椎高度明显低于A组(<0.05),B组伤椎丢失高度明显高于A组(<0.05)。两组术后1天及术后6个月VAS评分和ODI评分均较术前明显改善(<0.05),但两组间比较差异无统计学意义(>0.05)。

结论

单节段与双节段PKP治疗后壁破裂的OVCF均能获得满意疗效,但双节段PKP可能具有骨水泥渗漏率更低、高度丢失更少的优势。

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