Şişli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey.
The Council of Forensic Medicine, Istanbul, Turkey.
Int J Psychiatry Clin Pract. 2021 Mar;25(1):62-72. doi: 10.1080/13651501.2020.1833040. Epub 2020 Oct 16.
The aim of the study is to examine the relationship between anxiety and impulsivity and to reveal the correlation of these variables with clinical and sociodemographic features. It is also aimed to investigate the relationship between impulsivity and anxiety with neurocognitive functions in bipolar disorder.
The sample of the study comprises of 71 patients with bipolar disorder type I without any comorbidity (BD), 37 patients with anxiety disorder comorbidity with bipolar disorder type I (BDAD), 52 patients with anxiety disorder (AD) and 50 healthy controls (HC). Participants completed Barratt Impulsivity Scale-11, State-Trait Anxiety Inventory 1-2, Panic Disorder Severity Scale (PDSS), brief version of Fear of Negative Evaluation Scale (FNES), Anxiety Sensitivity Index-3 (ASI-3), Trail-Making Test A-B, Digit Span Test, Stroop Test.
PDSS scores, trait anxiety level, hypomanic and mixed episode numbers explain 26% of attention impulsivity. Gender and ASI-3 social dimensions explain 16% of motor impulsivity. Trait anxiety explains non-planning and total impulsivity at 26 and 24%, respectively. When neurocognitive impairment's effect was controlled, it was found AD and BDAD groups had higher impulsivity levels than the BD and HC groups.
Anxiety disorder comorbidity increases impulsivity in bipolar disorder.KEYPOINTSIn the presence of anxiety disorder spectrum comorbidity, bipolar disorder patients will have increased impulsivity and the clinical course may be more severe.Trait anxiety levels and anxiety sensitivity may be predictive factors for impulsivity.In the presence of anxiety disorder spectrum comorbidity, it should be taken into consideration that these patients may be more impulsive and should be treated with more care in terms of evaluation of the disorder.
本研究旨在探讨焦虑与冲动之间的关系，并揭示这些变量与临床和社会人口学特征的相关性。本研究还旨在调查双相障碍患者中冲动与焦虑与神经认知功能的关系。
本研究的样本包括 71 名无共病的 I 型双相障碍患者（BD）、37 名伴有 I 型双相障碍的焦虑障碍共病患者（BDAD）、52 名焦虑障碍患者（AD）和 50 名健康对照组（HC）。参与者完成了巴瑞特冲动量表-11、状态-特质焦虑量表 1-2、惊恐障碍严重程度量表（PDSS）、简短版负性评价恐惧量表（FNES）、焦虑敏感指数-3（ASI-3）、连线测验 A-B、数字跨度测验、斯特鲁普测验。
PDSS 评分、特质焦虑水平、轻躁狂和混合发作次数解释了注意冲动的 26%。性别和 ASI-3 社会维度解释了运动冲动的 16%。特质焦虑分别解释了非计划性和总冲动的 26%和 24%。当控制神经认知损伤的影响时，发现 AD 和 BDAD 组的冲动水平高于 BD 和 HC 组。
焦虑障碍谱系共病增加了双相障碍患者的冲动性。
在存在焦虑障碍谱系共病的情况下，双相障碍患者的冲动性会增加，且临床病程可能更为严重。特质焦虑水平和焦虑敏感性可能是冲动的预测因素。在存在焦虑障碍谱系共病的情况下，应考虑到这些患者可能更冲动，在评估该障碍时应更加小心。
