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2019冠状病毒病与心血管疾病:老年患者的特征

COVID-19 and cardiovascular disease: characteristic features in older patients.

作者信息

Boureau Anne-Sophie, de Decker Laure, Berrut Gilles, Hanon Olivier

机构信息

Pôle de gérontologie clinique, CHU de Nantes, Nantes, France, Université de Nantes, CHU Nantes, CNRS, Inserm, Institut du thorax, Nantes, France.

Pôle de gérontologie clinique, CHU de Nantes, Nantes, France.

出版信息

Geriatr Psychol Neuropsychiatr Vieil. 2020 Jun 1;18(2):141-148. doi: 10.1684/pnv.2020.0894.

Abstract

Coronavirus disease 2019 (COVID-19) is a secondary infectious disease caused by severe acute respiratory syndrome coronavirus 2. The link between cardiovascular disease and COVID-19 appears to be twofold. First, some reports indicate that certain groups of patients are at greater risk of COVID-19, including patients with cardiovascular risk factors, pre-existing cardiovascular conditions and older patients. In addition, the outcomes these patients face are disproportionately more severe. Second, SARS-CoV-2 infection can be complicated by life-threatening acute cardiovascular diseases. Despite the rapid ongoing evolution of information about this pandemic, this review aims to highlight cardiovascular pathologies related to COVID-19 as either comorbidities, including concerns and uncertainty regarding the effect of renin-angiotensin-aldosterone system (RAAS) inhibitors on angiotensin conversion enzyme 2, or cardiovascular complications.

摘要

2019冠状病毒病(COVID-19)是由严重急性呼吸综合征冠状病毒2引起的继发性传染病。心血管疾病与COVID-19之间的联系似乎是双重的。首先,一些报告表明,某些患者群体感染COVID-19的风险更高,包括有心血管危险因素、已患心血管疾病的患者以及老年患者。此外,这些患者面临的后果更为严重。其次,SARS-CoV-2感染可能并发危及生命的急性心血管疾病。尽管关于这场大流行的信息在迅速不断演变,但本综述旨在强调与COVID-19相关的心血管病理,无论是合并症,包括对肾素-血管紧张素-醛固酮系统(RAAS)抑制剂对血管紧张素转换酶2作用的担忧和不确定性,还是心血管并发症。

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