Dorantes-Acosta Elisa, Ávila-Montiel Diana, Klünder-Klünder Miguel, Juárez-Villegas Luis, Márquez-González Horacio
Biobanco de Investigación en Células Leucémicas. Hospital Infantil de México Federico Gómez, Mexico City, Mexico.
Investigación Clínica. Hospital Infantil de México Federico Gómez, Mexico City, Mexico.
Bol Med Hosp Infant Mex. 2020;77(5):234-241. doi: 10.24875/BMHIM.20000174.
Coronavirus disease (COVID)-19 has currently affected 8,015,502 million people worldwide with global mortality around 5%. Information in pediatric cancer patients is still limited, but it is emerging day by day. The objective of this scoping review was to analyze the available data associated with COVID-19 infection and mortality in pediatric cancer patients and to provide useful information to plan and design strategies in this group.
A search was conducted, and eight articles were obtained for qualitative analysis; 110 patients were included, all from cross-sectional studies. At the time of publication, all the analyzed documents reported no deaths associated with COVID-19.
According to the information, COVID-19 infection appears to be less severe in the pediatric population in comparison with adults and does not appear to be a cause of mortality in patients with childhood cancer.
Given the nature of preliminary reports and a short follow-up in cancer patients, it is necessary to have medium- and long-term follow-up studies to determine the effects of infection and modifications to the treatments of these patients.
冠状病毒病（COVID）-19目前已在全球感染80.15502亿人，全球死亡率约为5%。关于小儿癌症患者的信息仍然有限，但每天都在不断涌现。本范围综述的目的是分析与小儿癌症患者COVID-19感染和死亡率相关的现有数据，并为该群体制定和设计策略提供有用信息。
进行了检索，获得8篇文章进行定性分析；纳入110例患者，均来自横断面研究。在发表时，所有分析的文献均未报告与COVID-19相关的死亡病例。
根据这些信息，与成人相比，COVID-19感染在小儿人群中似乎不那么严重，并且似乎不是儿童癌症患者的死亡原因。
鉴于初步报告的性质以及癌症患者随访时间较短，有必要进行中长期随访研究，以确定感染的影响以及对这些患者治疗的调整。
