Shao Long, Wu Di, Li Jia-Ying, Wu Xiang-Dong, Zhou Xi, Qiu Gui-Xing, Luo Changqi, Xiao Peng-Cheng, Liu Jia-Cheng, Huang Wei
Department of Orthopaedic Surgery, Ningbo No.6 Hospital, Ningbo, Zhejiang, China.
Department of Orthopaedic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
BMJ Open. 2020 Oct 16;10(10):e037888. doi: 10.1136/bmjopen-2020-037888.
Anterior cruciate ligament (ACL) injury is one of the most common injuries of the knee. ACL reconstruction (ACLR) has been widely performed as a safe and effective treatment for ACL injuries. As there is an increasing trend in the incidence of ACL injury, hospital readmission after ACLR has attracted renewed attention for the financial burden to both patients and the healthcare system. However, information about hospital readmission after ACLR remains fragmented. Therefore, we plan to systematically review the literature to investigate the rate of, causes and risk factors for hospital readmission after ACLR, and summarise interventions to reduce hospital readmission. This article is to provide the protocol for an upcoming systematic review and meta-analysis on this important issue.
Reporting of this protocol follows the (PRISMA-P) checklist. Electronic databases, including PubMed, Embase and the Cochrane Library, will be systematically searched from inception to June 2020. No language restrictions will be applied. Studies will be included if they reported hospital readmission or explored the associated potential causes and risk factors for hospital readmission after ACLR. The primary outcome will be the number and time frame of hospital readmission after ACLR. Secondary outcomes will be reasons for readmission, number and types of complications, risk factors for readmission and preventive measures for readmission after ACLR. Quality assessments will be performed by using the Newcastle-Ottawa Scale (NOS). If possible, study results will be summarised in a forest plot, and heterogeneity will be tested by using the Cochran's Q and I statistics.
No ethical approval is required because our study is not related to patients or animals. The results will be published in a peer-reviewed journal.
CRD42020058624.
前交叉韧带（ACL）损伤是膝关节最常见的损伤之一。ACL重建术（ACLR）作为治疗ACL损伤的一种安全有效的方法已被广泛应用。由于ACL损伤的发病率呈上升趋势，ACLR后的医院再入院问题因给患者和医疗系统带来的经济负担而再次受到关注。然而，关于ACLR后医院再入院的信息仍然零散。因此，我们计划系统地回顾文献，以调查ACLR后医院再入院的发生率、原因和危险因素，并总结减少医院再入院的干预措施。本文旨在为即将进行的关于这一重要问题的系统评价和荟萃分析提供方案。
本方案的报告遵循系统评价和Meta分析方案的首选报告项目（PRISMA-P）清单。将从创刊至2020年6月对包括PubMed、Embase和Cochrane图书馆在内的电子数据库进行系统检索。不设语言限制。如果研究报告了医院再入院情况或探讨了ACLR后医院再入院的相关潜在原因和危险因素，则将其纳入。主要结局将是ACLR后医院再入院的次数和时间范围。次要结局将是再入院原因、并发症的数量和类型、再入院的危险因素以及ACLR后再入院的预防措施。将使用纽卡斯尔-渥太华量表（NOS）进行质量评估。如果可能，研究结果将汇总在森林图中，并使用Cochrane Q统计量和I统计量检验异质性。
由于我们的研究与患者或动物无关，因此无需伦理批准。研究结果将发表在同行评审期刊上。
PROSPERO注册号：CRD42020058624。
