Icon Cancer Center Gosford, Gosford, NSW, Australia.
Icon Cancer Centre Wahroonga, Wahroonga, NSW, Australia.
J Appl Clin Med Phys. 2020 Dec;21(12):27-42. doi: 10.1002/acm2.13056. Epub 2020 Oct 17.
Varian (Palo Alto, California, United States) recently released an online adaptation treatment platform, Ethos, which has introduced a new Dose Preview and Automated Plan Generation module despite sharing identical beam data with the existing Halcyon linac. The module incorporates a preconfigured beam model and the Acuros XB algorithm (Ethos AXB model) to generate final dose calculations from an initial fluence optimization. In this study, we comprehensively validated the accuracy of the Ethos AXB model by comparing it against the Halcyon AXB model, the Halcyon Anisotropic Analytical Algorithm (AAA) model, and measurements acquired on an Ethos linac. Results indicated that the Ethos AXB model demonstrated a comparable if not superior dosimetric accuracy to the Halcyon AXB model in basic and complex calculations, and at the same time its dosimetric accuracy in modulated and heterogeneous plans was better than that of the Halcyon AAA model. Despite the fact that the same algorithm was utilized, the Ethos AXB model and the Halcyon AXB model still exhibited variations across a range of tests, although these variations were predominantly insignificant in the clinical environment. The accuracy of the Ethos AXB model has been successfully verified in this study and is considered appropriate for the current clinical scope. On the basis of this study, clinical physicists can perform a data validation instead of a full data commissioning when implementing the Ethos system, thereby adopting a more efficient approach for Ethos installation.
瓦里安(美国加利福尼亚州帕洛阿尔托)最近发布了一款在线自适应治疗平台 Ethos,尽管与现有的 Halcyon 直线加速器共享相同的射束数据,但它引入了一个新的剂量预览和自动计划生成模块。该模块整合了一个预配置的射束模型和 Acuros XB 算法(Ethos AXB 模型),可以从初始的通量优化中生成最终的剂量计算。在这项研究中,我们通过将 Ethos AXB 模型与 Halcyon AXB 模型、Halcyon 各向异性解析算法(AAA)模型和在 Ethos 直线加速器上获得的测量结果进行比较,全面验证了 Ethos AXB 模型的准确性。结果表明,Ethos AXB 模型在基本和复杂计算中,其剂量学准确性与 Halcyon AXB 模型相当,如果不是更好的话,同时,其在调制和异质计划中的剂量学准确性优于 Halcyon AAA 模型。尽管使用了相同的算法,但 Ethos AXB 模型和 Halcyon AXB 模型在一系列测试中仍存在差异,尽管这些差异在临床环境中主要是微不足道的。在这项研究中,Ethos AXB 模型的准确性已经得到验证,适用于当前的临床范围。在此基础上,临床物理学家在实施 Ethos 系统时可以进行数据验证而不是全面的数据分析,从而为 Ethos 的安装采用更有效的方法。