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沙特阿拉伯1型糖尿病成年患者的胰岛素泵治疗问题:一项回顾性研究

Insulin Pump Therapy Issues Among Adults with Type 1 Diabetes Mellitus in Saudi Arabia: A Retrospective Study.

作者信息

Al-Saleh Yousef, Al Motairi Fajr, Hassan Esra, Al Sohaim Abdullah, Al Anazi Ibtisam, Al Masoud Ashwag, Al Wohabe Rasha, Al Anazi Sultana, Al Shahrani Awad, Al-Daghri Nasser M

机构信息

College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, 22490, Saudi Arabia.

King Abdullah International Medical Research Center, Riyadh, 11481, Saudi Arabia.

出版信息

Diabetes Ther. 2020 Dec;11(12):2993-3001. doi: 10.1007/s13300-020-00946-3. Epub 2020 Oct 17.

Abstract

INTRODUCTION

Type 1 diabetes mellitus (T1DM) is on the rise in Saudi Arabia. Management of T1DM is crucial in curbing the economic burden of this disease. Studies on insulin pump issues are scarce in the region. The present study aims to fill this gap.

METHODS

In this single-centre, retrospective study done in King Abdulaziz Medical City (KAMC) from March 2018 to March 2019, a total of 118 known Saudi T1DM adults (34 males and 84 females) were included. Data on demographics, glycated haemoglobin (HbA1c) and CSII use were collected.

RESULTS

The most common problem encountered by the patients on CSII was breaking down of the pump (30.0%), relocation of the cannula or tubing (22%) and air bubbles affecting delivery (16.1%). Eighty-one subjects (68.6%) claimed to have been admitted for DM management while on CSII. The use of CSII led to a significant reduction in HbA1c in all subjects (p < 0.001), but levels remain suboptimal. Only 53 subjects (44.9%) reported no significant problems in their CSII experience.

CONCLUSION

There is a high prevalence of T1DM adult patients experiencing device malfunctions and other issues while on CSII therapy. This may account for suboptimal improvement in the glycaemic control among T1DM Saudi patients. Issues on adherence and device malfunctions should be investigated further.

摘要

引言

沙特阿拉伯的1型糖尿病(T1DM)发病率正在上升。T1DM的管理对于控制这种疾病的经济负担至关重要。该地区关于胰岛素泵问题的研究很少。本研究旨在填补这一空白。

方法

在2018年3月至2019年3月于阿卜杜勒阿齐兹国王医疗城(KAMC)进行的这项单中心回顾性研究中,共纳入了118名已知患有T1DM的沙特成年患者(34名男性和84名女性)。收集了有关人口统计学、糖化血红蛋白(HbA1c)和持续皮下胰岛素输注(CSII)使用情况的数据。

结果

接受CSII治疗的患者遇到的最常见问题是泵故障(30.0%)、套管或管路移位(22%)以及影响输注的气泡(16.1%)。81名受试者(68.6%)称在接受CSII治疗期间因糖尿病管理而入院。CSII的使用使所有受试者的HbA1c显著降低(p<0.001),但水平仍未达到最佳。只有53名受试者(44.9%)报告在其CSII治疗经历中没有重大问题。

结论

T1DM成年患者在接受CSII治疗时出现设备故障和其他问题的患病率很高。这可能是沙特T1DM患者血糖控制改善未达最佳的原因。应进一步调查依从性和设备故障问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6719/7644598/5e9deb800738/13300_2020_946_Fig1_HTML.jpg

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