Al Hayek Ayman A, Robert Asirvatham A, Al Dawish Mohamed A, Braham Rim B, Goudeh Hanouf S, Al Sabaan Fahad S
Department of Endocrinology and Diabetes, Diabetes Treatment Center, Prince Sultan Military Medical City, Riyadh, Saudi Arabia,
Diabetes Ther. 2015 Jun;6(2):227-36. doi: 10.1007/s13300-015-0107-1. Epub 2015 Apr 30.
The aim of this study was to explore the impact of insulin pump therapy on diabetes treatment satisfaction and glycemic control among patients with type 1 diabetes mellitus (T1DM) in Saudi Arabia.
A 6-month, prospective study was conducted among 47 patients (aged 17-24 years) with T1DM who attended the Insulin Pump Clinic at Prince Sultan Military Medical City, Riyadh, Saudi Arabia, between April 2014 and November 2014. The respondents were purposively and conveniently selected and were interviewed using the Arabic version of the Diabetes Treatment Satisfaction Questionnaire at baseline, 3, and 6 months. Demographics and clinical variables including hemoglobin A1c (HbA1c) were also collected.
The mean (±standard deviation) age of the study cohort was 19.1 ± 1.93 years. Seventeen patients were male (36.2%) and 30 were female (63.8%). Compared to baseline, significant positive differences were found in treatment satisfaction among female patients and patients with long-standing T1DM at 6 months. Frequency of hyperglycemia and hypoglycemia declined significantly in female patients at 6 months and in patients who had a shorter duration of T1DM. Furthermore, significant positive differences were found in HbA1c levels among female patients and among those who had a shorter duration of T1DM compared to baseline. Both female and male patients and those with a shorter duration of T1DM showed a significant decline in insulin necessity at 6 months when compared to baseline.
Although multiple daily injections is a feasible preference for insulin supply, insulin pumps should also be considered for patients with T1DM as it appears to increase patients' treatment satisfaction, decrease the frequency of hypoglycemia, hyperglycemia, and reduce HbA1c levels.
本研究旨在探讨胰岛素泵治疗对沙特阿拉伯1型糖尿病（T1DM）患者糖尿病治疗满意度和血糖控制的影响。
2014年4月至2014年11月期间，对沙特阿拉伯利雅得苏丹王子军事医疗城胰岛素泵诊所的47例17至24岁的T1DM患者进行了为期6个月的前瞻性研究。通过目的性和便利性选择受访者，并在基线、3个月和6个月时使用阿拉伯语版糖尿病治疗满意度问卷进行访谈。还收集了包括糖化血红蛋白（HbA1c）在内的人口统计学和临床变量。
研究队列的平均（±标准差）年龄为19.1±1.93岁。17例为男性（36.2%），30例为女性（63.8%）。与基线相比，6个月时女性患者和长期患T1DM的患者在治疗满意度方面存在显著正差异。6个月时，女性患者以及T1DM病程较短的患者高血糖和低血糖的发生率显著下降。此外，与基线相比女性患者以及T1DM病程较短的患者在HbA1c水平上存在显著正差异。与基线相比，6个月时女性和男性患者以及T1DM病程较短的患者胰岛素需求量均显著下降。
尽管多次每日注射是胰岛素供应的一种可行选择，但对于T1DM患者也应考虑使用胰岛素泵，因为它似乎可以提高患者的治疗满意度，降低低血糖、高血糖的发生率，并降低HbA1c水平。
