肠道微生物群：肠道中的隐藏瑰宝？
Intestinal microbiota: The hidden gems in the gut?
机构信息
Pathogen Molecular Genetics Section, Laboratory of Bacteriology, National Institute of Allergy and Infectious Diseases, U.S. National Institutes of Health, 50 South Drive, Bethesda, Maryland 20814, USA.
Department of Biology, Georgetown University, Washington, DC, 20057, USA.
出版信息
Asian Pac J Allergy Immunol. 2020 Dec;38(4):215-224. doi: 10.12932/AP-020720-0897.
Within the last decade, our understanding of the role of the intestinal microbiota in health and disease has rapidly increased due to significant advances in next-generation sequencing technologies. Scientists have discovered more and more gut microbes with supposedly "beneficial" roles for human health and are starting to identify the underlying mechanisms. In this review, we summarize the latest knowledge about the human intestinal microbiota, including the intestinal bacteriome, virome and mycobiome. We discuss the function that recent studies attribute to the intestinal microbiota in preventing or controlling selected diseases and present recent research on biotherapeutic approaches to control these diseases.
在过去的十年中，由于下一代测序技术的显著进步，我们对肠道微生物群在健康和疾病中的作用的理解迅速增加。科学家们发现了越来越多的肠道微生物，它们对人类健康具有所谓的“有益”作用，并开始确定其潜在的机制。在这篇综述中，我们总结了有关人类肠道微生物群的最新知识，包括肠道细菌组、病毒组和真菌组。我们讨论了最近的研究认为肠道微生物群在预防或控制某些疾病方面的作用，并介绍了最近关于控制这些疾病的生物治疗方法的研究。
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