Department of Psychiatry, McGill University, Montréal, QC, Canada.
Douglas Research Centre, McGill University, 6875 Boul. Lasalle, Montréal, QC, H4H 1R3, Canada.
Int Arch Occup Environ Health. 2020 Nov;93(8):1013-1021. doi: 10.1007/s00420-020-01550-5. Epub 2020 May 14.
Job strain (high psychological demands and low decision control) has been associated with cardiovascular disease (CVD). It is unclear if job strain is associated with CVD risk score independently of depression, an established risk factor for CVD. This study investigated whether there is an association between job strain and CVD risk score, when depressive symptoms are controlled for. Sex differences were examined.
Data came from the CARTaGENE study, a community health survey of adults in Québec, Canada (n = 7848). Participants were working adults aged 40-69 years. CVD risk was estimated using the Framingham risk score. Job strain was measured as the ratio of job demands to control using the Job Content Questionnaire. Depressive symptoms were assessed using the Patient Health Questionnaire (PHQ-9). Regression analyses were conducted to examine the association between job strain and CVD risk score controlling for depressive symptoms. There was no interaction effect between job strain and depressive symptoms in the association with CVD risk score.
High job strain was reported in approximately 21% of participants, high Framingham risk score was observed in approximately 9%. Job strain was associated with the Framingham risk score (B = 0.73, p < 0.001, adjusted for age, sex, and education) and controlling for depressive symptoms did not significantly change the association (B = 0.59, p < 0.001).
The results suggest that the job strain is associated with CVD risk score and that this association is not explained by depressive symptoms. Similar associations were observed for males and females.
工作压力（高心理需求和低决策控制）与心血管疾病（CVD）有关。目前尚不清楚工作压力是否与抑郁（CVD 的既定风险因素）独立相关，与 CVD 风险评分有关。本研究调查了抑郁症状得到控制时，工作压力与 CVD 风险评分之间是否存在关联。并检验了性别差异。
数据来自 CARTaGENE 研究，这是一项针对加拿大魁北克成年人的社区健康调查（n=7848）。参与者为 40-69 岁的在职成年人。CVD 风险使用 Framingham 风险评分进行评估。工作压力使用工作内容问卷（Job Content Questionnaire）作为工作需求与控制的比值进行测量。抑郁症状使用患者健康问卷（PHQ-9）进行评估。回归分析用于检验工作压力与 CVD 风险评分之间的关联，同时控制抑郁症状的影响。在与 CVD 风险评分的关联中，工作压力与抑郁症状之间没有交互作用。
约 21%的参与者报告存在高工作压力，约 9%的参与者Framingham 风险评分较高。工作压力与 Framingham 风险评分相关（B=0.73，p<0.001，调整了年龄、性别和教育因素），控制抑郁症状后，这种关联没有显著变化（B=0.59，p<0.001）。
结果表明，工作压力与 CVD 风险评分有关，而这种关联不能用抑郁症状来解释。在男性和女性中均观察到类似的关联。
