Facultad de Ciencias de la Salud, Universidad San Jorge, Campus Universitario, Autov A23 km 299, 50830, Villanueva de Gállego, Zaragoza, Spain.
Departamento Química Física, Facultad de Ciencias, Instituto Agroalimentario de Aragón-IA2, Universidad de Zaragoza, 50009, Zaragoza, Spain.
Environ Sci Pollut Res Int. 2021 Feb;28(7):8812-8821. doi: 10.1007/s11356-020-11144-w. Epub 2020 Oct 18.
Most of the works carried out on deep eutectic solvents (DESs) make reference to their physicochemical properties, and the analysis of their toxicological behavior on the environment and biodegradability are still limited. In this work, an exhaustive study on the ecotoxicity of three pure deep eutectic solvents (reline, glyceline, and ethaline) and their mixtures with water (reline-water, glyceline-water, and ethaline-water) was carried out in different biomodels: bacteria (A. fisheri), crustaceans (D. magna), and algae (S. capricornatum). In addition, the amount of chlorophyll in the algae after exposure to the DESs was analyzed. Finally, the biodegradability of the studied DESs was also analyzed. The ecotoxic behavior strongly depends on both the biomodel tested and the presence of water in the mixture, resulting in low toxicities in all cases. Furthermore, most of the deep eutectic solvents studied can be considered readily biodegradable. A comparison of the ecotoxicity and biodegradability of these solvents under other conditions has also been provided, and a complete analysis is given.
大多数关于深共晶溶剂 (DESs) 的研究都参考了其物理化学性质，而对其环境毒理学行为和生物降解性的分析仍然有限。在这项工作中，我们在不同的生物模型中对三种纯深共晶溶剂（丙二醇、甘油和乙醇胺）及其与水的混合物（丙二醇-水、甘油-水和乙醇胺-水）进行了详尽的生态毒性研究：细菌（A. fisheri）、甲壳类动物（D. magna）和藻类（S. capricornatum）。此外，还分析了暴露在 DESs 后藻类中的叶绿素含量。最后，还分析了所研究的 DESs 的生物降解性。生态毒性行为强烈依赖于所测试的生物模型和混合物中是否存在水，结果在所有情况下毒性都较低。此外，大多数研究的深共晶溶剂都可以被认为是可快速生物降解的。还比较了在其他条件下这些溶剂的生态毒性和生物降解性，并进行了全面分析。
