[上海薏苡仁中玉米赤霉烯酮污染状况及其膳食暴露评估]

[Contamination of zearalenone and its dietary exposure assessment in coix seed in Shanghai].

作者信息

Zhu Yin, Mao Weifeng, Ji Shen, Long Tingting, Wang Shaomin, Ying Xuanyu, Miao Hong

机构信息

Yangtze Delta Region Institute of Tsinghua University, Jiaxing 314006, China.

Yangtze Delta Region Institute of Tsinghua University, Jiaxing 314006, China China National Center for Food Safety Risk Assessment, Beijing 100022, China.

出版信息

Wei Sheng Yan Jiu. 2020 Sep;49(5):840-872. doi: 10.19813/j.cnki.weishengyanjiu.2020.05.025.

DOI:10.19813/j.cnki.weishengyanjiu.2020.05.025

PMID:33070833

Abstract

OBJECTIVE

To analyze the zearalenone(ZEN) level in coix seed, and assess the risk of dietary exposure of ZEN in coix seed in Shanghai.

METHODS

The ZEN contents of 147 coix seed samples collected in Shanghai were determined. The consumption data of 730 adults in Shanghai was collected by questionnaire survey with random sampling method. Dietary intake of ZEN from coix seed in Shanghai was simulated by Monte Carlo simulation.

RESULTS

The total detection rate of ZEN in coix seed was 69. 39 %(102/147), with the content range of <1. 0-9361 μg/kg and the average value of 327. 7 μg/kg. The average exposure level of populations to ZEN in coix seed was 0. 0216 μg/(kg·d), which was much lower than the tolerable daily intake(TDI). The high exposure level(P95) of populations to ZEN in coix seed was 0. 0609 μg/(kg·d), which accounted for about 24% of TDI. There were about 1. 1% people with the dietary exposure to ZEN exceeding TDI on the basis of the ZEN contents in coix seed and consumption data of coix seed in Shanghai.

CONCLUSION

The health risk of ZEN exposure of coix seed in Shanghai population is lower when taking coix seed regularly, and there are potential health risks when taking coix seed highly contaminated with ZEN at a higher dose for a long time.

摘要

目的

分析薏苡仁中玉米赤霉烯酮（ZEN）含量，评估上海市居民食用薏苡仁的ZEN膳食暴露风险。

方法

测定上海市采集的147份薏苡仁样品中ZEN含量。采用随机抽样问卷调查法收集上海市730名成年人的消费数据。通过蒙特卡洛模拟法模拟上海市居民从薏苡仁中摄入ZEN的膳食情况。

结果

薏苡仁中ZEN总检出率为69.39%（102/147），含量范围为<1.0 - 9361μg/kg，平均值为327.7μg/kg。人群从薏苡仁中摄入ZEN的平均暴露水平为0.0216μg/（kg·d），远低于每日可耐受摄入量（TDI）。人群从薏苡仁中摄入ZEN的高暴露水平（P95）为0.0609μg/（kg·d），约占TDI的24%。基于上海市薏苡仁中ZEN含量和薏苡仁消费数据，约1.1%的人群膳食中ZEN暴露量超过TDI。