Conde-Antón Á, Hernando-Garijo I, Jiménez-Del-Barrio S, Mingo-Gómez M T, Medrano-de-la-Fuente R, Ceballos-Laita L
Facultad de Fisioterapia, Universidad de Valladolid, Soria, España.
Facultad de Fisioterapia, Universidad de Valladolid, Soria, España.
Neurologia (Engl Ed). 2020 Oct 15. doi: 10.1016/j.nrl.2020.07.024.
Fibromyalgia syndrome (FM) is a chronic pathology characterized by widespread pain commonly associated with psychological distress affecting quality of life. In recent years, transcranial direct current stimulation (tDCS) and transcranial magnetic stimulation (TMS) have been investigated to treat chronic pain. The aim of the current review is to determine the effects of tDCS and TMS on the main symptoms of patients with FM.
A systematic review based on PRISMA guidelines was carried out. The search strategy was performed in Medline, Scopus, PEDro and Cochrane Library. Randomized controlled trials based on the effects of tDCS and TMS on pain, pressure pain threshold, fatigue, anxiety and depression, catastrophizing and quality of life in patients with FM were analysed. Fourteen studies were included.
The application of tDCS to the motor cortex is the only intervention shown to decrease pain in the short and medium-term in patients with FM. The application of both interventions showed improvements in pressure pain threshold, catastrophizing and quality of life when applied to the motor cortex, and in fatigue when applied to the dorsolateral prefrontal cortex. The effects of these interventions on anxiety and depression are unclear.
纤维肌痛综合征（FM）是一种慢性疾病，其特征为广泛疼痛，通常与影响生活质量的心理困扰相关。近年来，经颅直流电刺激（tDCS）和经颅磁刺激（TMS）已被研究用于治疗慢性疼痛。本综述的目的是确定tDCS和TMS对FM患者主要症状的影响。
基于PRISMA指南进行了一项系统综述。检索策略在Medline、Scopus、PEDro和Cochrane图书馆中进行。分析了基于tDCS和TMS对FM患者疼痛、压痛阈值、疲劳、焦虑和抑郁、灾难化思维及生活质量影响的随机对照试验。共纳入14项研究。
将tDCS应用于运动皮层是唯一被证明能在短期和中期减轻FM患者疼痛的干预措施。当将这两种干预措施应用于运动皮层时，在压痛阈值、灾难化思维和生活质量方面有改善；当应用于背外侧前额叶皮层时，在疲劳方面有改善。这些干预措施对焦虑和抑郁的影响尚不清楚。
