Laboratory of Neurobiology, CIMES, University of Malaga, Malaga, Spain.
Department of Medicine, Faculty of Medicine, University of Malaga, Malaga, Spain.
CNS Neurosci Ther. 2022 Jan;28(1):5-18. doi: 10.1111/cns.13769. Epub 2021 Dec 3.
Brain stimulation has become one of the most acceptable therapeutic approaches in recent years and a powerful tool in the remedy against neurological diseases. Brain stimulation is achieved through the application of electric currents using non-invasive as well as invasive techniques. Recent technological advancements have evolved into the development of precise devices with capacity to produce well-controlled and effective brain stimulation. Currently, most used non-invasive techniques are repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS), whereas the most common invasive technique is deep brain stimulation (DBS). In last decade, application of these brain stimulation techniques has not only exploded but also expanded to wide variety of neurological disorders. Therefore, in the current review, we will provide an overview of the potential of both non-invasive (rTMS and tDCS) and invasive (DBS) brain stimulation techniques in the treatment of such brain diseases.
脑刺激已成为近年来最可接受的治疗方法之一,也是治疗神经疾病的有力工具。脑刺激是通过应用电流来实现的,既可以采用非侵入性技术,也可以采用侵入性技术。最近的技术进步已经发展成为开发能够产生精确控制和有效的脑刺激的精确设备。目前,最常用的非侵入性技术是重复经颅磁刺激(rTMS)和经颅直流电刺激(tDCS),而最常见的侵入性技术是深部脑刺激(DBS)。在过去十年中,这些脑刺激技术的应用不仅爆发式增长,而且还扩展到了多种神经疾病。因此,在当前的综述中,我们将概述非侵入性(rTMS 和 tDCS)和侵入性(DBS)脑刺激技术在治疗此类脑部疾病中的潜力。