口面部裂隙与心血管风险及疾病：因果关系与关联
OROFACIAL CLEFTS AND CARDIOVASCULAR RISK AND DISEASES: THE CAUSAL RELATIONSHIP AND ASSOCIATIONS.
作者信息
Nwaze C E, Adebayo O, Adeoye A M, Akinmoladun V
机构信息
College of Medicine, University of Ibadan, Ibadan.
Department of Medicine, University College Hospital, Ibadan.
出版信息
Ann Ib Postgrad Med. 2020 Jun;18(1):S28-S34.
Abstract
There is a complex interplay between orofacial clefts (OFCs) or cleft of the lip and palate and cardiovascular risk factors and cardiac diseases. The presence of maternal cardiovascular risk factors serves as a potent predisposing factor to the development of OFCs during foetal development in addition to the fact that various congenital anomalies are associated with OFCs either in syndromic or non-syndrome relationship. This article narratively explores this complex interplay, which is not uncommon.
摘要
口腔颌面部裂隙（OFCs），即唇腭裂，与心血管危险因素及心脏疾病之间存在复杂的相互作用。除了各种先天性异常与OFCs存在综合征性或非综合征性关联外，母亲的心血管危险因素是胎儿发育过程中OFCs发生的一个重要诱发因素。本文将对这种并不罕见的复杂相互作用进行叙述性探讨。
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