Pfannschmidt N, Krumholz K, Luderschmidt C
Z Hautkr. 1987 Jul 1;62(13):993-7.
A 40-year old female patient showed extended areas of homogeneous and verrucous leukoplakias on the floor of her mouth. In addition, we found leukoplakia of the speckled type on her right lower alveolar ridge. Histological examination of specimens taken from this region revealed squamous cell carcinoma with invasion into the mandibular bone. Heavy smoking as well as chronic irritation caused by a poorly fitted denture were considered predisposing factors. We carried out radical excision of the carcinoma and the verrucous leukoplakias including partial bone resection. During a follow-up period of two years, we did not observe any recurrences of the carcinoma.
一名40岁女性患者口腔底部出现大面积均匀性和疣状白斑。此外，我们在其右下牙槽嵴发现了斑点状白斑。对该区域采集的标本进行组织学检查显示为鳞状细胞癌，并侵犯下颌骨。大量吸烟以及不合适假牙引起的慢性刺激被认为是诱发因素。我们对癌组织和疣状白斑进行了根治性切除，包括部分骨切除。在两年的随访期内，我们未观察到癌组织复发。
