减少新冠病毒病的聚合酶链反应检测假阴性结果
Reducing False Negative PCR Test for COVID-19.
作者信息
Bahreini Fatemeh, Najafi Rezvan, Amini Razieh, Khazaei Salman, Bashirian Saeid
机构信息
Department of Molecular Medicine and Genetics, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Research Center for Molecular Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
出版信息
Int J MCH AIDS. 2020;9(3):408-410. doi: 10.21106/ijma.421. Epub 2020 Oct 8.
Abstract
As the SARS-CoV-2 (COVID-19) pandemic spreads rapidly, there is need for a diagnostic test with high accuracy to detect infected individuals especially those without symptoms. Real-time polymerase chain reaction (RT-PCR) is a common molecular test for diagnosing SARS-CoV-2. If some factors are not taken into consideration when performing this test, it can have a relatively large number of false negative results. In this article, we discuss important considerations that could lead to false negative test reduction.
摘要
随着严重急性呼吸综合征冠状病毒2（SARS-CoV-2，即新冠病毒）大流行迅速蔓延，需要一种具有高准确性的诊断测试来检测感染者，尤其是那些没有症状的人。实时聚合酶链反应（RT-PCR）是诊断SARS-CoV-2的一种常见分子检测方法。在进行这项检测时，如果不考虑某些因素，可能会产生相对较多的假阴性结果。在本文中，我们讨论了一些重要的注意事项，这些注意事项有助于减少检测的假阴性。
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