SARS-CoV-2 的遗传多样性与演化。
Genetic diversity and evolution of SARS-CoV-2.
机构信息
Division of Clinical Microbiology, University of Pittsburgh and University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
出版信息
Infect Genet Evol. 2020 Jul;81:104260. doi: 10.1016/j.meegid.2020.104260. Epub 2020 Feb 21.
COVID-19 is a viral respiratory illness caused by a new coronavirus called SARS-CoV-2. The World Health Organization declared the SARS-CoV-2 outbreak a global public health emergency. We performed genetic analyses of eighty-six complete or near-complete genomes of SARS-CoV-2 and revealed many mutations and deletions on coding and non-coding regions. These observations provided evidence of the genetic diversity and rapid evolution of this novel coronavirus.
新型冠状病毒肺炎（COVID-19）是一种由新型冠状病毒（SARS-CoV-2）引起的病毒性呼吸道疾病。世界卫生组织（WHO）宣布，SARS-CoV-2 疫情为全球公共卫生紧急事件。我们对 86 个 SARS-CoV-2 的完整或接近完整基因组进行了遗传分析，揭示了编码区和非编码区的许多突变和缺失。这些观察结果为这种新型冠状病毒的遗传多样性和快速进化提供了证据。
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