Zheng David D, Mantis Jazila, Gurung Dawa O, Abrudescu Adriana
Internal Medicine, Icahn School of Medicine at Mount Sinai, NYC Health + Hospitals/Queens, New York City, USA.
Infectious Disease, Icahn School of Medicine at Mount Sinai, NYC Health + Hospitals/Queens, New York City, USA.
Cureus. 2020 Sep 14;12(9):e10455. doi: 10.7759/cureus.10455.
Extraintestinal manifestations (EIM) in inflammatory bowel disease (IBD) are common including cutaneous manifestations that either precede or follow manifestations of IBD. Cutaneous manifestations of IBD include erythema nodosum, pyoderma gangrenosum, oral lesions, and Sweet's syndrome. Cutaneous manifestations of IBD tend to recur and extensive cases may require maintenance management with immunomodulators or biologics. However, the complications and adverse effects of long-term therapy with immunosuppressive agents are numerous and need to be considered before their initiation. We report a case of a Crohn's disease patient with recurrent and debilitating cutaneous manifestation of lupus panniculitis that had sustained remission with hydroxychloroquine.
炎症性肠病（IBD）的肠外表现（EIM）很常见，包括在IBD表现之前或之后出现的皮肤表现。IBD的皮肤表现包括结节性红斑、坏疽性脓皮病、口腔病变和Sweet综合征。IBD的皮肤表现往往会复发，广泛的病例可能需要用免疫调节剂或生物制剂进行维持治疗。然而，免疫抑制剂长期治疗的并发症和不良反应众多，在开始治疗前需要加以考虑。我们报告一例克罗恩病患者，其反复出现使人衰弱的狼疮性脂膜炎皮肤表现，使用羟氯喹后病情持续缓解。
