使用自动便携式泵（Zyklomat），通过慢性脉冲式给予促性腺激素释放激素（GnRH），诱导受原发性下丘脑闭经影响的正常雄激素水平女性排卵。
Induction of ovulation in normo-androgenic women, affected by primary hypothalamic amenorrhea, with chronic pulsatile administration of GnRH, using an automatic portable pump (Zyklomat).
作者信息
Amodeo G, Palermo R, Gabrielli M, Girasolo A
出版信息
Acta Eur Fertil. 1987 Mar-Apr;18(2):113-5.
PMID:3307262
Abstract
Pulsatile administration of GnRH appears to be the most rational and physiological treatment of infertility in patients affected by hypothalamic amenorrhea. The authors conclude that the results obtained with this method of treatment in patients with severe hypothalamic amenorrhea suggest that the choice of pulsatile GnRH therapy is an effective and practical method for induction of ovulation.
摘要
脉冲式给予促性腺激素释放激素（GnRH）似乎是治疗下丘脑性闭经患者不孕症最合理且符合生理的方法。作者得出结论，在重度下丘脑性闭经患者中采用这种治疗方法所获得的结果表明，选择脉冲式GnRH疗法是诱导排卵的一种有效且实用的方法。
相似文献
1
2
GNRH therapy in hypothalamic primary amenorrhea.
Acta Eur Fertil. 1988 May-Jun;19(3):149-53.
3
[Induction of ovulation using pulsatile GnRH administration to infertile females].
Wien Klin Wochenschr. 1986 Jul 18;98(14):461-5.
4
Polycystic ovarian disease unmasked by pulsatile GnRH therapy in a subgroup of women with hypothalamic amenorrhea.在一小部分下丘脑性闭经女性中，脉冲式促性腺激素释放激素治疗揭示了多囊卵巢疾病。
Fertil Steril. 2008 Feb;89(2):404-9. doi: 10.1016/j.fertnstert.2007.02.063. Epub 2007 Jun 21.
5
Pulsatile intravenous GnRH treatment in hypothalamic amenorrhea.脉冲式静脉注射促性腺激素释放激素治疗下丘脑性闭经。
Acta Eur Fertil. 1991 Nov-Dec;22(6):333-4.
6
7
LHRH treatment of hypothalamic amenorrhoea.
Acta Med Hung. 1986;43(2):223-8.
8
Induction of ovulation and fertility in amenorrheic women by pulsatile low-dose gonadotropin-releasing hormone.
N Engl J Med. 1984 Apr 26;310(17):1069-74. doi: 10.1056/NEJM198404263101702.
9
[Induction of ovulation and pregnancy resulting from chronic and pulsatile administration of gonadotropin-releasing-hormone (Gn-RH)].[促性腺激素释放激素（Gn-RH）的慢性和脉冲式给药诱导排卵及妊娠]
J Gynecol Obstet Biol Reprod (Paris). 1982;11(4):505-8.
10
[Treatment of sterility of hypothalamic origin by pulsatile injection of GnRH. Use of a portable pump].
Sem Hop. 1983 Oct 20;59(37-38):2638-9.
Zotero 插件