Cao Xuefeng, Brouwers Jos F H M, van Dijk Linda, van de Lest Chris H A, Parker Craig T, Huynh Steven, van Putten Jos P H, Kelly David J, Wösten Marc M S M
Department of Biomolecular Health Sciences, Utrecht University, 3584 CL Utrecht, the Netherlands.
Produce Safety and Microbiology Research Unit, Agricultural Research Service, U.S. Department of Agriculture, Albany, California 94710, USA.
Data Brief. 2020 Sep 28;33:106349. doi: 10.1016/j.dib.2020.106349. eCollection 2020 Dec.
The membrane phospholipid composition is not a stable bacterial characteristic but can change in response to altered environmental conditions. Here we provide the dataset of the phospholipidome and transcriptome of the microaerophilic human pathogen under different environmental conditions. These data have been used in (2020), The unique phospholipidome of the enteric pathogen : Lysolipids are required for motility at low oxygen availability. Here the abundance of each phospholipid is shown during the growth of for 0-108 h under low and high oxygen conditions (0.3 vs 10% O). The phospholipid data were obtained by applying high performance liquid chromatography tandem-mass spectrometry (LC-MS/MS). The transcriptomic data obtained by RNA-seq show the differential expressed genes between logarithmic and stationary grown bacteria. In addition, our data might serve as a reference information for further in-depth investigation to understand the relation between specific phospholipids and the activity of membrane associated proteins.
膜磷脂组成并非细菌的稳定特征，而是会随环境条件的改变而变化。在此，我们提供了微需氧人类病原体在不同环境条件下的磷脂组和转录组数据集。这些数据已用于（2020年）《肠道病原体的独特磷脂组：溶血磷脂是低氧条件下运动所必需的》一文。此处展示了在低氧和高氧条件（0.3%对10% O₂）下该病原体生长0至108小时期间每种磷脂的丰度。磷脂数据通过应用高效液相色谱串联质谱法（LC-MS/MS）获得。通过RNA测序获得的转录组数据显示了对数生长期和稳定期细菌之间的差异表达基因。此外，我们的数据可能为进一步深入研究以了解特定磷脂与膜相关蛋白活性之间的关系提供参考信息。
