Department of Clinical Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran.
Iranian Society of Anesthesiology and Critical Care, Department of Critical Care Medicine, Islamic Azad University Tehran Medical Branch, Tehran, Iran.
JPEN J Parenter Enteral Nutr. 2021 Sep;45(7):1504-1513. doi: 10.1002/jpen.2031. Epub 2020 Dec 9.
There are no data on the validity of the modified Nutrition Risk in the Critically Ill (m-NUTRIC)-score and Nutritional Risk Screening 2002 (NRS-2002)-score in Iranian intensive care unit (ICU) patients. The Malnutrition Universal Screening Tool (MUST) is still used in most Iranian ICUs. Our goal was to test the validity of these tools in the Iranian ICU population.
The association between nutrition risk scores and outcomes (longer length of stay [LOS], prolonged mechanical ventilation [MV], and 28-day mortality) was assessed using the multivariable logistic regression. The performance of nutrition risk tools to predict 28-day mortality was assessed using the receiver operating characteristic curve. A logistic regression model was used to test the interaction between nutrition risk category, energy adequacy, and 28-day mortality.
Four hundred forty patients were included. Both the m-NUTRIC and NRS-2002 scores were significantly associated with all 3 outcomes (all P < .001). However, no significant association was identified between the MUST and all 3 outcomes (P > .05). The area under the curve for predicting 28-day mortality was 0.806 (95% CI, 0.756-0.851), 0.695 (95% CI, 0.632-0.752), and 0.551 (95% CI, 0.483-0.612) for m-NUTRIC, NRS-2002, and MUST, respectively. Greater energy adequacy was associated with a lower 28-day mortality rate in patients with high m-NUTRIC but not in those with low m-NUTRIC score (P interaction = .015).
In the Iranian ICU population, the m-NUTRIC score may be a valid tool for identifying patients who would benefit from more aggressive nutrition therapy.
目前尚无关于改良营养风险在危重症患者中的有效性的资料(m-NUTRIC 评分)和营养风险筛查 2002(NRS-2002)评分在伊朗重症监护病房(ICU)患者中的数据。在大多数伊朗 ICU 中,仍然使用营养不良通用筛查工具(MUST)。我们的目标是测试这些工具在伊朗 ICU 人群中的有效性。
使用多变量逻辑回归评估营养风险评分与结局(更长的住院时间 [LOS]、延长机械通气 [MV]和 28 天死亡率)之间的关联。使用受试者工作特征曲线评估营养风险工具预测 28 天死亡率的性能。使用逻辑回归模型检验营养风险类别、能量充足性和 28 天死亡率之间的交互作用。
共纳入 440 例患者。m-NUTRIC 和 NRS-2002 评分均与所有 3 个结局显著相关(均 P<.001)。然而,MUST 与所有 3 个结局均无显著相关性(P>.05)。预测 28 天死亡率的曲线下面积分别为 m-NUTRIC 评分 0.806(95%CI,0.756-0.851)、0.695(95%CI,0.632-0.752)和 0.551(95%CI,0.483-0.612);NRS-2002 评分和 MUST。在 m-NUTRIC 评分高的患者中,能量充足性与较低的 28 天死亡率相关,但在 m-NUTRIC 评分低的患者中则无相关性(P 交互=.015)。
在伊朗 ICU 人群中,m-NUTRIC 评分可能是一种有效工具,可用于识别需要更积极营养治疗的患者。