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衣物机洗后异噻唑啉酮的持久性。

Persistence of Isothiazolinones in Clothes After Machine Washing.

出版信息

Dermatitis. 2021;32(5):298-300. doi: 10.1097/DER.0000000000000603.

Abstract

BACKGROUND

Sensitization to methylchloroisothiazolinone (MCI) and methylisothiazolinone (MI) is a worldwide problem. Washing machine detergents are suspected to cause cutaneous symptoms in highly sensitized patients. Little is known about the persistence of isothiazolinones in clothes that have been washed.

OBJECTIVE

The aim of the study was to analyze the possible persistence of MI, MCI, benzisothiazolinone, and octylisothiazolinone in common fabrics after machine washing.

METHODS

Different clothes (cotton, polyester, linen, and wool) were collected, and 4 types of wash were done (control, standard, standard + conditioner, and standard + double rinse). The samples were analyzed using ultrahigh-performance liquid chromatography.

RESULTS

The results showed that the concentrations of isothiazolinones were very low, independent of the type of material or wash. The highest levels were found in the control wash (hand wash), reaching a maximum of 0.4 ppm in the linen.

CONCLUSIONS

Our findings suggest that it is not necessary to recommend that patients sensitized to MI avoid isothiazolinones in machine detergents or fabric conditioners or to double rinse. However, after using the detergent for hand washing (the control in our study), there may remain sufficient concentrations of isothiazolinones in clothes to produce symptoms in highly sensitized patients.

摘要

背景

甲基氯异噻唑啉酮(MCI)和甲基异噻唑啉酮(MI)致敏是一个全球性问题。洗衣机清洁剂被怀疑会导致高度敏感患者出现皮肤症状。关于已洗过的衣物中异噻唑啉酮的持续存在,知之甚少。

目的

本研究旨在分析洗衣机洗涤后常见织物中 MI、MCI、苯并异噻唑啉酮和辛基异噻唑啉酮的可能残留情况。

方法

收集不同的衣物(棉、聚酯、亚麻和羊毛),进行 4 种洗涤(对照、标准、标准+调理剂和标准+双冲洗)。使用超高效液相色谱法对样品进行分析。

结果

结果表明,异噻唑啉酮的浓度非常低,与材料或洗涤类型无关。在对照洗涤(手洗)中发现的水平最高,亚麻中最高可达 0.4ppm。

结论

我们的研究结果表明,没有必要建议对 MI 敏感的患者避免在洗衣机清洁剂或织物调理剂中使用异噻唑啉酮,或进行双冲洗。然而,在用清洁剂进行手洗(我们研究中的对照)后,衣物中可能仍残留足够浓度的异噻唑啉酮,从而导致高度敏感患者出现症状。

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