Spece Laura J, Epler Eric M, Duan Kevin, Donovan Lucas M, Griffith Matthew F, LaBedz Stephanie, Thakur Neeta, Wiener Renda Soylemez, Krishnan Jerry A, Au David H, Feemster Laura C
Health Services Research and Development, Veterans Affairs Puget Sound Health Care System, Seattle, Washington.
Division of Pulmonary, Critical Care, and Sleep Medicine, University of Washington, Seattle, Washington.
Ann Am Thorac Soc. 2021 Mar;18(3):426-432. doi: 10.1513/AnnalsATS.202004-364OC.
Hypoxemia associated with acute exacerbations of chronic obstructive pulmonary disease (COPD) often resolves with time. Current guidelines recommend that patients recently discharged with supplemental home oxygen after hospitalization should not have renewal of the prescription without assessment for hypoxemia. Understanding patterns of home oxygen reassessment is an opportunity to improve quality and value in home oxygen prescribing and may provide future targets for deimplementation. We sought to measure the frequency of home oxygen reassessment within 90 days of hospitalization for COPD and determine the potential population eligible for deimplementation. We performed a cohort study of patients ≥40 years hospitalized for COPD at five Veterans Affairs facilities who were prescribed home oxygen at discharge. Our primary outcome was the frequency of reassessment within 90 days by oxygen saturation (Sp) measurement. Secondary outcomes included the proportion of patients potentially eligible for discontinuation (Sp > 88%) and patients in whom oxygen was discontinued. Our primary exposures were treatment with long-acting bronchodilators, prior history of COPD exacerbation, smoking status, and pulmonary hypertension. We used a mixed-effects Poisson model to measure the association between patient-level variables and our outcome, clustered by site. We also performed a positive deviant analysis using chart review to uncover system processes associated with high-quality oxygen prescribing. A total of 287 of 659 (43.6%; range 24.8-78.5% by site) patients had complete reassessment within 90 days. None of our patient-level exposures were associated with oxygen reassessment. Nearly half of those with complete reassessment were eligible for discontinuation on the basis of Medicare guidelines (43.2%; = 124/287). When using the newest evidence available by the Long-Term Oxygen Treatment Trial, most of the cohort did not have resting hypoxemia (84.3%; 393/466) and would be eligible for discontinuation. The highest-performing Veterans Affairs facility had four care processes to support oxygen reassessment and discontinuation, versus zero to one at all other sites. Fewer than half of patients prescribed home oxygen after a COPD exacerbation are reassessed within 90 days. New system processes supporting timely reassessment and discontinuation of unnecessary home oxygen therapy could improve the quality and value of care.
慢性阻塞性肺疾病(COPD)急性加重期相关的低氧血症通常会随时间缓解。当前指南建议,近期住院后在家接受补充氧气治疗的患者,若未进行低氧血症评估,则不应续签氧气处方。了解家庭氧气重新评估模式是提高家庭氧气处方质量和价值的契机,还可能为减少不必要的治疗提供未来目标。我们试图衡量COPD患者住院90天内家庭氧气重新评估的频率,并确定可能适合减少不必要治疗的人群。我们对在五个退伍军人事务机构因COPD住院且出院时开具家庭氧气处方的40岁及以上患者进行了队列研究。我们的主要结局是通过血氧饱和度(Sp)测量在90天内重新评估的频率。次要结局包括可能符合停用条件(Sp>88%)的患者比例以及已停用氧气的患者。我们的主要暴露因素包括长效支气管扩张剂治疗、COPD既往加重史、吸烟状况和肺动脉高压。我们使用混合效应泊松模型来衡量患者层面变量与结局之间的关联,并按地点进行聚类。我们还通过病历审查进行了正向偏差分析,以发现与高质量氧气处方相关的系统流程。659名患者中有287名(43.6%;各地点范围为24.8 - 78.5%)在90天内完成了重新评估。我们的患者层面暴露因素均与氧气重新评估无关。根据医疗保险指南,近一半完成重新评估的患者符合停用条件(43.2%;124/287)。根据长期氧疗试验的最新证据,大多数队列患者没有静息性低氧血症(84.3%;393/466),符合停用条件。表现最佳的退伍军人事务机构有四个支持氧气重新评估和停用的护理流程,而其他所有地点为零至一个。COPD急性加重后开具家庭氧气处方的患者中,不到一半在90天内接受了重新评估。支持及时重新评估和停用不必要家庭氧疗的新系统流程可以提高护理质量和价值。