Key Laboratory of Luminescence Analysis and Molecular Sensing (Southwest University), Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, PR China.
Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University), Chongqing Science and Technology Bureau, College of Pharmaceutical Science, Southwest University, Chongqing, 400715, PR China.
Talanta. 2021 Jan 1;221:121498. doi: 10.1016/j.talanta.2020.121498. Epub 2020 Aug 6.
Due to the ultra-weak and instantaneous chemiluminescence (CL) of luminol-HO system, developing new catalysts to dramatically enhance and produce persistent CL emission is crucial. In this study, the Cu-metal-organic frameworks (Cu-MOFs) with flower morphology converted from Cu-based metal-organic gels (Cu-MOGs) could catalyze luminol-HO system, exhibiting persistent CL. The possible mechanism of this persistent emission of luminol was attributed to the gradual generation of OH˙, O˙ and O in Cu-MOFs-catalyzed luminol-HO system. In addition, OH˙ and O˙- were continuously recombined into singlet oxygen on the surface of Cu-MOFs which further prolonged the duration time of the CL leading to the persistent emission, due to the longer lifetime of O compared to OH˙ and O˙. Furthermore, based on the high-intensity emission of Cu-MOFs-catalyzed luminol-HO system, the strategy for sensitive response to quercetin was established with good linearity within the range of 0.05-1.2 μM and a detection limit of 49.7 nM. This study provides a new idea for developing persistent CL catalysts.
由于鲁米诺-HO 体系的超弱和瞬时化学发光（CL），开发新的催化剂来显著增强和产生持久的 CL 发射至关重要。在这项研究中，由铜基金属有机凝胶（Cu-MOGs）转化而成的具有花状形态的 Cu 金属有机骨架（Cu-MOFs）可以催化鲁米诺-HO 体系，表现出持久的 CL。这种鲁米诺持续发光的可能机制归因于在 Cu-MOFs 催化的鲁米诺-HO 体系中逐渐生成 OH˙、O˙和 O。此外，由于 O 的寿命比 OH˙和 O˙长，因此 OH˙和 O˙-在 Cu-MOFs 表面上不断重新组合成单线态氧，这进一步延长了 CL 的持续时间，导致持续发光。此外，基于 Cu-MOFs 催化的鲁米诺-HO 体系的高强度发射，建立了一种基于鲁米诺-HO 体系的高灵敏度响应槲皮素的策略，在 0.05-1.2 μM 的范围内具有良好的线性关系，检测限为 49.7 nM。这项研究为开发持久 CL 催化剂提供了新的思路。
