丙型肝炎病毒感染会增加医护人员的疲劳感。

Hepatitis C Virus Infection Increases Fatigue in Health Care Workers.

作者信息

Catania Vito Emanuele, Malaguarnera Giulia, Fiorenza Giorgia, Chisari Eleonora Margherita, Lipari Anna Rita, Gallina Valentino, Pennisi Manuela, Lanza Giuseppe, Malaguarnera Michele

机构信息

Department of Medical, Surgical Sciences and Advanced Technologies "G.F. Ingrassia", University of Catania, 95124 Catania, Italy.

"The Great Senescence" Research Centre, University of Catania, 95100 Catania, Italy.

出版信息

Diseases. 2020 Oct 15;8(4):37. doi: 10.3390/diseases8040037.

DOI:10.3390/diseases8040037

PMID:33076215

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7709099/

Abstract

Fatigue is a common state associated with a weakening or depletion of one's physical and mental resources, that leads to the inability to continue the individual functioning at a normal level of activity. Frequently, fatigue represents a response to infections, inflammation and autoimmune diseases. The scope of this study was to evaluate the fatigue in healthcare workers with and without hepatitis C virus (HCV) infection. Mental, physical and severity fatigue were evaluated through Krupp, Wessely and Powell fatigue scale. Anti-HCV antibodies, HCV RNA and HCV genotypes were also measured. Physical, mental and severity fatigue were higher in healthcare workers with HCV infection than the healthcare workers without infection ( < 0.01). Our data showed a direct link between fatigue and HCV infection in healthcare workers. Further studies are needed to evaluate HCV antiviral treatments on fatigue severity and on quality of life in healthcare workers.

摘要

疲劳是一种常见状态，与个人身心资源的削弱或耗尽相关，导致无法在正常活动水平上持续个人功能。疲劳常常是对感染、炎症和自身免疫性疾病的一种反应。本研究的范围是评估感染和未感染丙型肝炎病毒（HCV）的医护人员的疲劳情况。通过克虏伯、韦塞利和鲍威尔疲劳量表评估精神、身体和严重程度疲劳。还检测了抗-HCV抗体、HCV RNA和HCV基因型。感染HCV的医护人员的身体、精神和严重程度疲劳高于未感染的医护人员（<0.01）。我们的数据表明医护人员的疲劳与HCV感染之间存在直接联系。需要进一步研究来评估HCV抗病毒治疗对医护人员疲劳严重程度和生活质量的影响。