• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

智能感应笔辅助动态笔迹分析诊断帕金森病。

Intelligent Sensory Pen for Aiding in the Diagnosis of Parkinson's Disease from Dynamic Handwriting Analysis.

机构信息

Graduate Program in Applied Informatics (PPGIA), University of Fortaleza, Fortaleza 60811-905, Ceará, Brazil.

LASIGE, Department of Computer Science, Faculty of Sciences, University of Lisbon, Campo Grande, 1749-016 Lisbon, Portugal.

出版信息

Sensors (Basel). 2020 Oct 15;20(20):5840. doi: 10.3390/s20205840.

DOI:10.3390/s20205840
PMID:33076436
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7602671/
Abstract

In this paper, we propose a pen device capable of detecting specific features from dynamic handwriting tests for aiding on automatic Parkinson's disease identification. The method used in this work uses machine learning to compare the raw signals from different sensors in the device coupled to a pen and extract relevant information such as tremors and hand acceleration to diagnose the patient clinically. Additionally, the datasets composed of raw signals from healthy and Parkinson's disease patients acquired here are made available to further contribute to research related to this topic.

摘要

本文提出了一种笔式设备,能够从动态手写测试中检测特定特征,以辅助帕金森病的自动识别。本工作中使用的方法采用机器学习技术,比较笔式设备中不同传感器的原始信号,并提取相关信息,如震颤和手部加速度,以进行临床诊断。此外,还提供了由健康患者和帕金森病患者的原始信号组成的数据集,以进一步促进与该主题相关的研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d62/7602671/0030a966b9ef/sensors-20-05840-g017.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d62/7602671/6ee9e880401f/sensors-20-05840-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d62/7602671/214a245f8a04/sensors-20-05840-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d62/7602671/b06bae4a63a1/sensors-20-05840-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d62/7602671/c2d73379d185/sensors-20-05840-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d62/7602671/e3c45309b5b8/sensors-20-05840-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d62/7602671/9fb235dfb69d/sensors-20-05840-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d62/7602671/0912bd07b3dc/sensors-20-05840-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d62/7602671/737c6defccba/sensors-20-05840-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d62/7602671/cea5c51c7e6f/sensors-20-05840-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d62/7602671/a997b9acf492/sensors-20-05840-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d62/7602671/dcfbea7dabac/sensors-20-05840-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d62/7602671/fc7b61754f58/sensors-20-05840-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d62/7602671/00c20694a141/sensors-20-05840-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d62/7602671/061d8023ed7b/sensors-20-05840-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d62/7602671/f1584f5ddbcf/sensors-20-05840-g015.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d62/7602671/caa25c1b9556/sensors-20-05840-g016.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d62/7602671/0030a966b9ef/sensors-20-05840-g017.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d62/7602671/6ee9e880401f/sensors-20-05840-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d62/7602671/214a245f8a04/sensors-20-05840-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d62/7602671/b06bae4a63a1/sensors-20-05840-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d62/7602671/c2d73379d185/sensors-20-05840-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d62/7602671/e3c45309b5b8/sensors-20-05840-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d62/7602671/9fb235dfb69d/sensors-20-05840-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d62/7602671/0912bd07b3dc/sensors-20-05840-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d62/7602671/737c6defccba/sensors-20-05840-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d62/7602671/cea5c51c7e6f/sensors-20-05840-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d62/7602671/a997b9acf492/sensors-20-05840-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d62/7602671/dcfbea7dabac/sensors-20-05840-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d62/7602671/fc7b61754f58/sensors-20-05840-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d62/7602671/00c20694a141/sensors-20-05840-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d62/7602671/061d8023ed7b/sensors-20-05840-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d62/7602671/f1584f5ddbcf/sensors-20-05840-g015.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d62/7602671/caa25c1b9556/sensors-20-05840-g016.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d62/7602671/0030a966b9ef/sensors-20-05840-g017.jpg

相似文献

1
Intelligent Sensory Pen for Aiding in the Diagnosis of Parkinson's Disease from Dynamic Handwriting Analysis.智能感应笔辅助动态笔迹分析诊断帕金森病。
Sensors (Basel). 2020 Oct 15;20(20):5840. doi: 10.3390/s20205840.
2
Analysis and evaluation of handwriting in patients with Parkinson's disease using kinematic, geometrical, and non-linear features.使用运动学、几何和非线性特征分析和评估帕金森病患者的笔迹。
Comput Methods Programs Biomed. 2019 May;173:43-52. doi: 10.1016/j.cmpb.2019.03.005. Epub 2019 Mar 13.
3
A New Approach to Diagnose Parkinson's Disease Using a Structural Cooccurrence Matrix for a Similarity Analysis.使用结构共现矩阵进行相似性分析的帕金森病诊断新方法。
Comput Intell Neurosci. 2018 Apr 24;2018:7613282. doi: 10.1155/2018/7613282. eCollection 2018.
4
Handwritten dynamics assessment through convolutional neural networks: An application to Parkinson's disease identification.基于卷积神经网络的手写动力学评估:在帕金森病识别中的应用。
Artif Intell Med. 2018 May;87:67-77. doi: 10.1016/j.artmed.2018.04.001. Epub 2018 Apr 16.
5
Early diagnosis of Parkinson's disease using Continuous Convolution Network: Handwriting recognition based on off-line hand drawing without template.基于连续卷积网络的帕金森病早期诊断:基于无模板离线手绘的笔迹识别。
J Biomed Inform. 2022 Jun;130:104085. doi: 10.1016/j.jbi.2022.104085. Epub 2022 Apr 29.
6
Bag of Samplings for computer-assisted Parkinson's disease diagnosis based on Recurrent Neural Networks.基于循环神经网络的计算机辅助帕金森病诊断的抽样袋。
Comput Biol Med. 2019 Dec;115:103477. doi: 10.1016/j.compbiomed.2019.103477. Epub 2019 Oct 4.
7
The Rehapiano-Detecting, Measuring, and Analyzing Action Tremor Using Strain Gauges.利用应变片检测、测量和分析复健钢琴演奏者的动作震颤。
Sensors (Basel). 2020 Jan 24;20(3):663. doi: 10.3390/s20030663.
8
Standardized handwriting to assess bradykinesia, micrographia and tremor in Parkinson's disease.用于评估帕金森病中运动迟缓、小写症和震颤的标准化笔迹。
PLoS One. 2014 May 22;9(5):e97614. doi: 10.1371/journal.pone.0097614. eCollection 2014.
9
On the use of histograms of oriented gradients for tremor detection from sinusoidal and spiral handwritten drawings of people with Parkinson's disease.基于方向梯度直方图的帕金森病患者正弦和螺旋手写笔迹震颤检测
Med Biol Eng Comput. 2021 Jan;59(1):195-214. doi: 10.1007/s11517-020-02303-9. Epub 2021 Jan 7.
10
A novel approach combining temporal and spectral features of Arabic online handwriting for Parkinson's disease prediction.一种结合阿拉伯语在线手写的时间和频谱特征用于帕金森病预测的新方法。
J Neurosci Methods. 2020 Jun 1;339:108727. doi: 10.1016/j.jneumeth.2020.108727. Epub 2020 Apr 13.

引用本文的文献

1
Inter-rater reliability of hand motor function assessment in Parkinson's disease: Impact of clinician training.帕金森病手部运动功能评估的评分者间信度:临床医生培训的影响。
Clin Park Relat Disord. 2024 Oct 28;11:100278. doi: 10.1016/j.prdoa.2024.100278. eCollection 2024.
2
Upper limb intention tremor assessment: opportunities and challenges in wearable technology.上肢意向性震颤评估:可穿戴技术的机遇与挑战。
J Neuroeng Rehabil. 2024 Jan 13;21(1):8. doi: 10.1186/s12984-023-01302-9.
3
Interpol questioned documents review 2019-2022.

本文引用的文献

1
Deep Learning for Multigrade Brain Tumor Classification in Smart Healthcare Systems: A Prospective Survey.深度学习在智能医疗系统中多等级脑肿瘤分类中的应用:前瞻性调查。
IEEE Trans Neural Netw Learn Syst. 2021 Feb;32(2):507-522. doi: 10.1109/TNNLS.2020.2995800. Epub 2021 Feb 4.
2
Smart Supervision of Cardiomyopathy Based on Fuzzy Harris Hawks Optimizer and Wearable Sensing Data Optimization: A New Model.基于模糊哈里斯鹰优化器和可穿戴传感数据优化的心肌病智能监测:一种新模型。
IEEE Trans Cybern. 2021 Oct;51(10):4944-4958. doi: 10.1109/TCYB.2020.3000440. Epub 2021 Oct 12.
3
Automatic Neuroimage Processing and Analysis in Stroke-A Systematic Review.
国际刑警组织对2019年至2022年文件的审查
Forensic Sci Int Synerg. 2023 Feb 24;6:100300. doi: 10.1016/j.fsisyn.2022.100300. eCollection 2023.
4
Diagnosis and Treatment of Tremor in Parkinson's Disease Using Mechanical Devices.使用机械设备诊断和治疗帕金森病震颤
Life (Basel). 2022 Dec 27;13(1):78. doi: 10.3390/life13010078.
5
Analysis of Parkinson's Disease Using an Imbalanced-Speech Dataset by Employing Decision Tree Ensemble Methods.使用决策树集成方法对不均衡语音数据集进行帕金森病分析。
Diagnostics (Basel). 2022 Nov 30;12(12):3000. doi: 10.3390/diagnostics12123000.
6
Patients' Self-Report and Handwriting Performance Features as Indicators for Suspected Mild Cognitive Impairment in Parkinson's Disease.患者的自我报告和书写表现特征可作为帕金森病疑似轻度认知障碍的指标。
Sensors (Basel). 2022 Jan 12;22(2):569. doi: 10.3390/s22020569.
脑卒中的自动神经影像处理与分析——系统综述。
IEEE Rev Biomed Eng. 2020;13:130-155. doi: 10.1109/RBME.2019.2934500. Epub 2019 Aug 23.
4
A survey on computer-assisted Parkinson's Disease diagnosis.计算机辅助帕金森病诊断研究综述。
Artif Intell Med. 2019 Apr;95:48-63. doi: 10.1016/j.artmed.2018.08.007. Epub 2018 Sep 7.
5
Handwritten dynamics assessment through convolutional neural networks: An application to Parkinson's disease identification.基于卷积神经网络的手写动力学评估:在帕金森病识别中的应用。
Artif Intell Med. 2018 May;87:67-77. doi: 10.1016/j.artmed.2018.04.001. Epub 2018 Apr 16.
6
Human Activity Recognition from Body Sensor Data using Deep Learning.基于深度学习的人体传感器数据活动识别。
J Med Syst. 2018 Apr 16;42(6):99. doi: 10.1007/s10916-018-0948-z.
7
Digitized Spiral Drawing: A Possible Biomarker for Early Parkinson's Disease.数字化螺旋绘图:早期帕金森病的一种可能生物标志物。
PLoS One. 2016 Oct 12;11(10):e0162799. doi: 10.1371/journal.pone.0162799. eCollection 2016.
8
Distinguishing Parkinson's disease from atypical parkinsonian syndromes using PET data and a computer system based on support vector machines and Bayesian networks.利用正电子发射断层扫描(PET)数据以及基于支持向量机和贝叶斯网络的计算机系统区分帕金森病与非典型帕金森综合征。
Front Comput Neurosci. 2015 Nov 5;9:137. doi: 10.3389/fncom.2015.00137. eCollection 2015.
9
Computational approaches for understanding the diagnosis and treatment of Parkinson's disease.用于理解帕金森病诊断与治疗的计算方法。
IET Syst Biol. 2015 Dec;9(6):226-33. doi: 10.1049/iet-syb.2015.0030.
10
Unsupervised learning based feature extraction for differential diagnosis of neurodegenerative diseases: A case study on early-stage diagnosis of Parkinson disease.基于无监督学习的特征提取用于神经退行性疾病的鉴别诊断:帕金森病早期诊断的案例研究
J Neurosci Methods. 2015 Dec 30;256:30-40. doi: 10.1016/j.jneumeth.2015.08.011. Epub 2015 Aug 21.