Zheng W L, Zhang H, Zhang S, Shen C F, Wang C, Wang D Z, Song G D, Jiang G H
Tianjin Centers for Disease Control and Prevention, Tianjin 300011, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2020 Sep 10;41(9):1477-1481. doi: 10.3760/cma.j.cn112338-20191018-00741.
To analyze the trends of mortality and years of life lost (YLL) of breast cancer in women in Tianjin and provide references for the development of intervention strategies. The crude mortality rate, standard mortality rate, cumulative rate (0-74 years old) and truncated rate (35-64 years old) of breast cancer in women in Tianjin from 1999 to 2017 were calculated. The annual percentage change of the mortality rate and YLL rate were analyzed by Joinpoint regression. From 1999 to 2017, a total of 8 356 deaths of breast cancer were reported in Tianjin, resulting in a YLL of 262 835.53 person-years. The average crude mortality rate was 9.15/100 000. The average age standardized rate(ASR) (World) was 6.14/100 000. The ratio of ASR (World) between urban and rural areas was 1.73∶1. The peak mortality ratio of age groups between urban area and rural area was 3.13∶1. From 1999 to 2017, both the crude mortality rate and ASR of breast cancer in Tianjin had rising trends. In 2017, the crude mortality rate and the ASR of breast cancer increased by 113.7% and 44.4% respectively compared with 1999. The increase of urban mortality mainly came from elderly group aged ≥75 years, and the mortality of young age groups in rural area showed an fast increases, which was most obvious in age group 45-59 years (average annual percentage change=3.6%, <0.01). The mortality rate of breast cancer and disease burden in women in Tianjin are still in rapid increase. We should continue to implement the prevention and control strategies such as lifestyle intervention and screening of key groups. More attention need to be paid to the increase of breast cancer incidence in rural area.
分析天津市女性乳腺癌死亡率及寿命损失年数（YLL）的变化趋势，为制定干预策略提供参考。计算了1999年至2017年天津市女性乳腺癌的粗死亡率、标准死亡率、累积率（0至74岁）和截缩率（35至64岁）。采用Joinpoint回归分析死亡率和YLL率的年度变化百分比。1999年至2017年，天津市共报告8356例乳腺癌死亡病例，导致262835.53人年的YLL。平均粗死亡率为9.15/10万。平均年龄标准化率（世界）为6.14/10万。城乡地区年龄标准化率（世界）之比为1.73∶1。城乡地区年龄组死亡率峰值之比为3.13∶1。1999年至2017年，天津市乳腺癌粗死亡率和年龄标准化率均呈上升趋势。2017年，乳腺癌粗死亡率和年龄标准化率分别比1999年增长了113.7%和44.4%。城市死亡率的上升主要来自75岁及以上老年组，农村地区年轻年龄组死亡率呈快速上升趋势，在45至59岁年龄组最为明显（平均年度变化百分比=3.6%，P<0.01）。天津市女性乳腺癌死亡率和疾病负担仍在快速上升。应继续实施生活方式干预和重点人群筛查等防控策略。需更加关注农村地区乳腺癌发病率的上升。
