Department of Dietetics, Faculty of Human Nutrition and Consumer Sciences, Warsaw University of Life Sciences (WULS - SGGW) , Warsaw, Poland.
Expert Rev Endocrinol Metab. 2020 Sep;15(5):355-362. doi: 10.1080/17446651.2020.1813020. Epub 2020 Oct 20.
As men age, progressive testosterone deficiency syndrome becomes an increasingly common problem. However, the decreased testosterone levels are not only the result of advanced age.
PubMed search of published data on testosterone, nutritional deficiency, stress, sleep, and obesity. Many factors impact the male HPG axis (the hypothalamic-pituitary-adrenal), including body weight, calorific and nutritional value of a diet, the amount and quality of sleep, as well as the level of stress. In the case of persons of healthy weight, a below-average calorific value of a diet may decrease the levels of testosterone in men. On the other hand, the same caloric deficiency in obese persons may result in a neutral or positive impact on testosterone levels.
Many factors, including external, environmental and internal factors, influence testosterone levels. Undoubtedly, nutritional deficiency, and particularly of such nutrients as zinc, magnesium, vitamin D, together with low polyphenols intake, affects the HPG axis. The levels of mental and oxidative stress can also adversely impact the axis. Hence, a diagnosis of the cause of disturbance in testosterone levels depends on many factors and requires a broad range of research, as well as a change of patients' lifestyle.
随着男性年龄的增长，进行性睾丸激素缺乏综合征成为一个越来越常见的问题。然而，睾丸激素水平的降低不仅是年龄增长的结果。
PubMed 上已发表的关于睾丸激素、营养缺乏、压力、睡眠和肥胖的研究数据进行了检索。许多因素会影响男性的 HPG 轴（下丘脑-垂体-肾上腺），包括体重、饮食的热量和营养价值、睡眠的数量和质量，以及压力水平。在健康体重的人群中，饮食的热量值低于平均水平可能会降低男性的睾丸激素水平。另一方面，肥胖人群的相同热量缺乏可能对睾丸激素水平产生中性或积极的影响。
许多因素，包括外部、环境和内部因素，都会影响睾丸激素水平。毫无疑问，营养缺乏，特别是锌、镁、维生素 D 等营养素的缺乏，以及多酚类物质摄入不足，都会影响 HPG 轴。精神和氧化应激水平也会对该轴产生不利影响。因此，睾丸激素水平紊乱的诊断取决于许多因素，需要广泛的研究，以及改变患者的生活方式。
