Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Cukurova University, Adana, Turkey.
Department of Internal Medicine, Department of Endokrine, Faculty of Medicine, Cukurova University, Adana, Turkey.
Rheumatol Int. 2024 Oct;44(10):2111-2115. doi: 10.1007/s00296-023-05470-8. Epub 2023 Oct 14.
Sexual health is an important part of a healthy life. The aim of this study is to define Behçet's sexual dysfunction and the factors affecting it. Sixty-nine patients with Behçet's disease (BD) and 74 healthy controls were included in the study. International Index of Erectile Function (IIEF), the Female Sexual Function Index (FSFI), the Beck Depression Inventory (BDI), and the Short Form Health Survey (SF-36) were filled out by patients and healthy control group (HCG). Follicle-stimulating hormone (FSH), luteinizing hormone (LH), prolactin and estradiol or testosterone levels according to gender were measured in Behçet's patients. The rate of sexual dysfunction and its relationship with gonadal hormones, Beck depression and SF 36 subgroups were evaluated in Behçet's patients. Sixty-nine patients with BD (mean age 39.55 ± 11.7) and 74 HCG (mean age 36.9 ± 6.84) were included in the study. Sexual dysfunction was observed in 74% (49) of BD and 59.5% (44) of HCG (p = 0.047). Prolactin level is within normal limits in all patients. Although there are abnormal levels of gonadal hormones, no relationship was found with sexual dysfunction. Depression especially is more prevalent compared to the healthy population (p = 0.016). The presence of depression negatively affects sexual life. Depression, SF 36 physical role limitations, energy vitality, vitality and mental health were associated with sexual dysfunction in patients with Behçet's disease. Sexual dysfunction was associated with the presence of depression and SF-36 subscales in Behçet's patients.
性健康是健康生活的重要组成部分。本研究旨在定义贝切特病的性功能障碍及其影响因素。本研究纳入了 69 例贝切特病（BD）患者和 74 例健康对照组（HCG）。患者和健康对照组填写国际勃起功能指数（IIEF）、女性性功能指数（FSFI）、贝克抑郁量表（BDI）和健康调查简表 36 项（SF-36）。根据性别测量贝切特病患者的卵泡刺激素（FSH）、黄体生成素（LH）、催乳素和雌二醇或睾酮水平。评估贝切特病患者的性功能障碍发生率及其与性腺激素、贝克抑郁和 SF-36 亚组的关系。本研究纳入了 69 例 BD 患者（平均年龄 39.55±11.7）和 74 例 HCG（平均年龄 36.9±6.84）。BD 患者中 74%（49 例）存在性功能障碍，HCG 中 59.5%（44 例）存在性功能障碍（p=0.047）。所有患者的催乳素水平均在正常范围内。尽管性腺激素水平异常，但与性功能障碍无关。与健康人群相比，抑郁更为普遍（p=0.016）。抑郁的存在会对性生活产生负面影响。抑郁、SF-36 身体角色受限、精力活力、活力和心理健康与贝切特病患者的性功能障碍有关。抑郁和 SF-36 亚组与贝切特病患者的性功能障碍有关。
