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一名17个月大免疫功能正常儿童并发眼眶曲霉病和毛霉病

Concomitant orbital aspergillosis and mucormycosis in a 17 months old immunocompetent child.

作者信息

Habroosh Fatima A, Eatamadi Habibullah, Mohamed Rawia M

机构信息

Sheikh Khalifa Medical City, United Arab Emirates.

出版信息

Saudi J Ophthalmol. 2017 Jul-Sep;31(3):193-195. doi: 10.1016/j.sjopt.2017.05.006. Epub 2017 May 17.

DOI:10.1016/j.sjopt.2017.05.006
PMID:28860923
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5569355/
Abstract

Isolated multiple orbital fungal infection (aspergillosis & mucormycosis) is extremely rare disease in immunocompetent individuals and especially in children. Placement of prosthetic device during the surgery could be one of the risk factors. The presentation is usually masquerading other entities which make early diagnosis a challengeable. This case presenting a 17 months old immunocompetent child who is diagnosed with isolated multiple orbital fungal infection: aspergillosis & mucormycosis. The presentation was mimicking orbital cellulitis and chronic dacryocystitis. The definitive diagnosis was made by tissue biopsy. The child was managed by surgical debridement and IV amphotericin B liposomal. High index of suspicion to fungal infection should be considered after surgical intervention with insertion prosthetic materials. To the best of our knowledge, orbital aspergillosis in immunocompetent young children is exceptionally rare.

摘要

孤立性多发性眼眶真菌感染(曲霉菌病和毛霉菌病)在免疫功能正常的个体中极为罕见,在儿童中尤其如此。手术过程中植入假体装置可能是危险因素之一。其表现通常会伪装成其他病症,这使得早期诊断具有挑战性。本病例为一名17个月大的免疫功能正常儿童,被诊断为孤立性多发性眼眶真菌感染:曲霉菌病和毛霉菌病。其表现类似眼眶蜂窝织炎和慢性泪囊炎。通过组织活检做出了明确诊断。该患儿接受了手术清创和静脉注射两性霉素B脂质体治疗。在手术中植入假体材料后,应高度怀疑真菌感染。据我们所知,免疫功能正常的幼儿眼眶曲霉菌病极为罕见。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcc2/5569355/e6ed941aada2/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcc2/5569355/2225f3f3fde8/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcc2/5569355/d3d0375f7e64/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcc2/5569355/e6ed941aada2/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcc2/5569355/2225f3f3fde8/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcc2/5569355/d3d0375f7e64/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcc2/5569355/e6ed941aada2/gr3.jpg

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