Department of Clinical Oncology, Prince of Wales Hospital, the Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China.
Division of Epidemiology, the Jockey Club School of Public Health and Primary Care, the Chinese University of Hong Kong, New Territories, Hong Kong SAR, China.
BMC Cancer. 2020 Oct 19;20(1):1013. doi: 10.1186/s12885-020-07517-6.
To compare change in level of physical activity between pre-and post- diagnosis of breast cancer in Chinese women.
Based on an on-going prospective study consisting of a sample of Chinese women with breast cancer, a validated modified Chinese Baecke questionnaire was used to measure physical activity at baseline (12 months before cancer diagnosis), 18-, 36- and 60-months after diagnosis (over the previous 12 months before each interview).
In our cohort of 1462 Chinese women with a mean age of 52 years, the mean level of physical activity at post-diagnosis was 9.6 metabolic equivalent of task (MET)-hours/week, which was significantly higher than that at pre-diagnosis with mean level of 5.9 MET-hours/week (P < 0.001). The mean levels of physical activity at 18-, 36- and 60-months follow-up were 9.9, 9.8 and 9.3 MET-hours/week, respectively. There was no significant difference between any two of the three follow-ups at post-diagnosis. The proportions of participant who met World Cancer Research Fund/ American Institute for Cancer Research (WCRF/AICR) recommendation before and after cancer diagnosis were both low, being 20.7 and 35.1%, respectively. Compared to pre-diagnosis, most of the patients improved or had no change on level of physical activity at post-diagnosis, with the respective proportion being 48.2 and 43.8%.
Adherence to current lifestyle recommendation for cancer survivors, Chinese women with breast cancer significantly increased level of physical activity level after cancer diagnosis, and such improvement was sustained to 5 years post-diagnosis. The proportion of patients who met the exercise recommendation for cancer survivors was still low. Encouraging patients on the importance of durable high level of physical activity in breast cancer survivorship is warranted.
比较中国女性乳腺癌诊断前后身体活动水平的变化。
基于一项正在进行的前瞻性研究，该研究纳入了一组中国乳腺癌女性患者，使用经过验证的改良中文版 Baecke 问卷，在基线（癌症诊断前 12 个月）、诊断后 18 个月、36 个月和 60 个月（每次访谈前 12 个月）时测量身体活动。
在我们的 1462 名平均年龄为 52 岁的中国女性队列中，诊断后身体活动的平均水平为 9.6 代谢当量任务（MET）小时/周，明显高于诊断前的 5.9 MET 小时/周（P < 0.001）。诊断后 18、36 和 60 个月随访时的平均水平分别为 9.9、9.8 和 9.3 MET 小时/周。在诊断后三个随访时间点之间没有显著差异。在诊断前后，符合世界癌症研究基金会/美国癌症研究所（WCRF/AICR）建议的参与者比例均较低，分别为 20.7%和 35.1%。与诊断前相比，大多数患者在诊断后身体活动水平有所提高或保持不变，分别占 48.2%和 43.8%。
中国乳腺癌女性在癌症诊断后，坚持当前针对癌症幸存者的生活方式建议，显著增加了身体活动水平，且这种改善持续到诊断后 5 年。符合癌症幸存者运动建议的患者比例仍然较低。有必要鼓励患者在乳腺癌生存期间保持持久的高水平身体活动。
