Del-Rosal-Jurado Alicia, Romero-Galisteo Rita, Trinidad-Fernández Manuel, González-Sánchez Manuel, Cuesta-Vargas Antonio, Ruiz-Muñoz Maria
Department of Physiotherapy, Institute of Biomedicine of Málaga (IBIMA), Clinimetric Group (F-14), Chair of Physiotherapy and Disability, Faculty of Health Sciences, Andalucía Tech, University of Málaga, 29071 Málaga, Spain.
Department of Physiotherapy, Faculty of Health Sciences, Andalucía Tech, University of Málaga, 29071 Málaga, Spain.
J Clin Med. 2020 Apr 24;9(4):1239. doi: 10.3390/jcm9041239.
Advances achieved in diagnosis and improvements in treatment for breast cancer have resulted in a favourable survival rate. Therapeutic physical exercise (TPE) is presented as an intervention strategy that seeks to improve the functional capabilities of the subject. To analyse if clinical practice guidelines recommend therapeutic physical exercise to reduce the adverse effects of treatment in breast cancer survivors, and on what level of scientific evidence are these recommendations based. This systematic review was prepared by searching nine electronic databases to identify eligible studies. Thirteen met the criteria for inclusion. The Appraisal of Guidelines for Research and Evaluation (AGREE II) scale was used to analyse the quality of Clinical Practice Guideline (CPGs). The percentages obtained ranged between 30.07% and 75.70%. Specifically, the highest degree of evidence could be found in the application of TPE to offset adverse effects leading to effects such as: an increase in the quality of life, fatigue reduction, and reduction in body weight alterations. TPE is presented as an optimal intervention strategy to alleviate the negative effects that patients with breast cancer suffer as a result of the treatments received. The level of evidence that supports this claim is very strong for the majority of the side effects analysed. However, this evidence is not always included in the clinical practice guidelines.
乳腺癌诊断方面取得的进展以及治疗方法的改进带来了良好的生存率。治疗性体育锻炼(TPE)作为一种干预策略,旨在提高患者的功能能力。分析临床实践指南是否推荐治疗性体育锻炼以减轻乳腺癌幸存者治疗的不良反应,以及这些推荐基于何种科学证据水平。本系统评价通过检索九个电子数据库来识别 eligible 研究。十三个研究符合纳入标准。使用研究与评价指南评估(AGREE II)量表来分析临床实践指南(CPG)的质量。获得的百分比在30.07%至75.70%之间。具体而言,在应用TPE以抵消不良反应从而产生诸如生活质量提高、疲劳减轻和体重变化减少等效果方面,可以找到最高程度的证据。TPE被视为减轻乳腺癌患者因接受治疗而遭受的负面影响的最佳干预策略。对于所分析的大多数副作用,支持这一说法的证据水平非常高。然而,这一证据并不总是包含在临床实践指南中。