Effect of quorum sensing and quenching molecules on inter-kingdom biofilm formation by and bacteria.

The ecology of a biofilm is a complex function of different factors, including the presence of microbial metabolites excreted by the inhabitants of the biofilm. This study aimed to assess the effect of patulin, and -(3-oxododecanoyl)-L-homoserine lactone (3-oxo-C-HSL) on inter-kingdom biofilm formation between a filamentous fungus and bacteria isolated from drinking water. The filamentous fungus and the bacteria and were used as model species. biofilm formation and development was more susceptible to the presence of the quenching molecules than biofilms. Patulin reduced biofilm growth while 3-oxo-C-HSL caused an increase after 48 h. The presence of had a detrimental effect on cell numbers, while an advantageous effect was observed with The overall results reveal that quorum sensing and quenching molecules have a significant effect on inter-kingdom biofilm formation, especially on bacterial numbers.