Tang Xiusong, Chen Jing, Ou Peiqi, Chen Jingqin, Lan Shaohang, Luo Jiajing, Luo Yehao, Shang Yuzhi, Fang Gang
Guangxi university of Traditional Chinese Medicine, Nanning, Guangxi Province, China.
Medicine (Baltimore). 2020 Oct 16;99(42):e22698. doi: 10.1097/MD.0000000000022698.
Endometriosis (EMT) is one of the common diseases of women of childbearing age. EMT destroys the anatomical structure of the pelvis, which leads to abnormal ovulation and endocrine abnormalities. It also affects embryo implantation and makes patients infertile. Recently, it is confirmed that Chinese medicine also have an excellent clinical efficacy on EMT. Compared with the conventional western medicine treatment, it effectively relieve pain and other concomitant symptoms.
The following databases will be searched for relevant information before July 2020: PubMed, Embase, Cochrane Library, Web of Science, and CNKI.
the overall effective rate, VAS score.
blood serum estradiol (E2), progesterone (P), Follicle-Stimulating Hormone (FSH), adverse events. Data will be collected independently by 2 researchers, and the risk of bias in meta-analysis will be evaluated according to "Cochrane Handbook for Systematic Reviews of Interventions". All data analysis will be conducted using Review Manager V.5.3. and Stata V.12.0.
The curative effect and safety of Chinese herbal compound prescription treatment for EMT patients will be evaluated systematically.
The systematic review of this study will summarize the currently published evidence of Chinese herbal compound prescription treatment for EMT to further guide its promotion and application.
The private information from individuals will not be published. This systematic review also will not involve endangering participant rights. Ethical approval is not required. The results may be published in a peer-reviewed journal or disseminated in relevant conferences. OPEN SCIENCE FRAMEWORK (OSF) REGISTRATION NUMBER:: https://osf.io/p5nrk.
子宫内膜异位症（EMT）是育龄期女性的常见疾病之一。EMT破坏盆腔的解剖结构，导致排卵异常和内分泌紊乱。它还会影响胚胎着床，导致患者不孕。近年来，证实中药对EMT也有良好的临床疗效。与传统西医治疗相比，能有效缓解疼痛等伴随症状。
在2020年7月前检索以下数据库以获取相关信息：PubMed、Embase、Cochrane图书馆、Web of Science和中国知网。
总有效率、视觉模拟评分（VAS）。
血清雌二醇（E2）、孕酮（P）、促卵泡生成素（FSH）、不良事件。数据将由2名研究人员独立收集，并根据《Cochrane系统评价干预措施手册》评估荟萃分析中的偏倚风险。所有数据分析将使用Review Manager V.5.3和Stata V.12.0进行。
将系统评价中药复方制剂治疗EMT患者的疗效和安全性。
本研究的系统评价将总结目前已发表的中药复方制剂治疗EMT的证据，以进一步指导其推广应用。
不会公布个人隐私信息。本系统评价也不会涉及危及参与者权益的问题。无需伦理批准。结果可能发表在同行评审期刊上或在相关会议上传播。开放科学框架（OSF）注册号：https://osf.io/p5nrk 。
