Xie Xinglei, Liu Jiaming, Pujol Isabel, López Alicia, Martínez María José, García-Patterson Apolonia, Adelantado Juan M, Ginovart Gemma, Corcoy Rosa
Departament de Medicina, Universitat Autònoma de Barcelona, Bellaterra, 08193 Barcelona, Spain.
Servei d'Endocrinologia i Nutrició, Hospital de la Santa Creu i Sant Pau, 08041 Barcelona, Spain.
J Clin Med. 2020 Oct 18;9(10):3343. doi: 10.3390/jcm9103343.
In the care of women with gestational diabetes mellitus (GDM), more attention is put on glycemic control than in factors such as gestational weight gain (GWG). We aimed to evaluate the rate of inadequate GWG in women with GDM, its clinical predictors and the association with pregnancy outcomes.
Cohort retrospective analysis.
GWG according to Institute of Medicine 2009 and 18 pregnancy outcomes. Clinical characteristics were considered both as GWG predictors and as covariates in outcome prediction.
descriptive, multinomial and logistic regression.
We assessed 2842 women diagnosed with GDM in the 1985-2011 period. GWG was insufficient (iGWG) in 50.3%, adequate in 31.6% and excessive (eGWG) in 18.1%; length of follow-up for GDM was positively associated with iGWG. Overall pregnancy outcomes were satisfactory. GWG was associated with pregnancy-induced hypertension, preeclampsia, cesarean delivery and birthweight-related outcomes. Essentially, the direction of the association was towards a higher risk with eGWG and lower risk with iGWG (i.e., with Cesarean delivery and excessive growth).
In this cohort of women with GDM, inadequate GWG was very common at the expense of iGWG. The associations with pregnancy outcomes were mainly towards a higher risk with eGWG and lower risk with iGWG.
在妊娠糖尿病(GDM)女性的护理中,相较于诸如孕期体重增加(GWG)等因素,人们更多地关注血糖控制。我们旨在评估GDM女性中GWG不足的发生率、其临床预测因素以及与妊娠结局的关联。
队列回顾性分析。
根据医学研究所2009年标准的GWG以及18种妊娠结局。临床特征既被视为GWG的预测因素,也被视为结局预测中的协变量。
描述性、多项和逻辑回归分析。
我们评估了1985年至2011年期间诊断为GDM的2842名女性。GWG不足(iGWG)的占50.3%,充足的占31.6%,过量(eGWG)的占18.1%;GDM的随访时间与iGWG呈正相关。总体妊娠结局令人满意。GWG与妊娠高血压、子痫前期、剖宫产以及与出生体重相关的结局有关。本质上,这种关联的方向是eGWG时风险较高,iGWG时风险较低(即剖宫产和过度生长)。
在这组GDM女性中,GWG不足非常常见,以iGWG为代价。与妊娠结局的关联主要是eGWG时风险较高,iGWG时风险较低。