Han Kyunghee, Kwak Dong Wook, Ryu Hyun Mee, Park Hyun-Young
Division of Population Health Research, Department of Precision Medicine, Korea National Institute of Health, Korea Disease Control and Prevention Agency, Cheongju, Korea.
Department of Obstetrics and Gynecology, Ajou University School of Medicine, Suwon, Korea.
Osong Public Health Res Perspect. 2022 Aug;13(4):242-251. doi: 10.24171/j.phrp.2022.0182. Epub 2022 Aug 31.
This study investigated whether weight was managed appropriately in pregnant women with gestational diabetes mellitus (GDM) and examined the association between insufficient gestational weight gain (GWG) and adverse pregnancy outcomes.
The study included 235 pregnant women with GDM from the Korean Pregnancy Outcome Study. GWG from the second to the third trimester (kg/wk) and total GWG (kg) were classified as insufficient, appropriate, or excessive according to the 2009 Institute of Medicine guidelines. Adverse pregnancy outcomes included maternal (hypertensive disorders of pregnancy, preterm birth, cesarean delivery, and delivery complications) and infant (low birth weight, high birth weight, neonatal intensive care unit admission, and congenital anomalies) outcomes.
The proportion of pregnant women with GDM who had insufficient GWG from the second to the third trimester was 52.3%, and that of participants with total insufficient GWG was 48.1%. There were no significant associations between insufficient GWG from the second to the third trimester and adverse pregnancy outcomes. Participants with total insufficient GWG had a significantly lower risk of preterm birth (odds ratio [OR], 0.17; 95% confidence interval [CI], 0.05-0.60) and high birth weight (OR, 0.23; 95% CI, 0.07-0.80).
Our findings suggest the importance of appropriate weight management and the need for GWG guidelines for pregnant women with GDM.
本研究调查了妊娠期糖尿病（GDM）孕妇的体重是否得到适当管理，并探讨了孕期体重增加不足（GWG）与不良妊娠结局之间的关联。
该研究纳入了来自韩国妊娠结局研究的235名患有GDM的孕妇。根据2009年医学研究所的指南，将孕中期到孕晚期的GWG（千克/周）和总GWG（千克）分为不足、适当或过多。不良妊娠结局包括母体结局（妊娠高血压疾病、早产、剖宫产和分娩并发症）和婴儿结局（低出生体重、高出生体重、新生儿重症监护病房入院和先天性异常）。
孕中期到孕晚期GWG不足的GDM孕妇比例为52.3%，总GWG不足的参与者比例为48.1%。孕中期到孕晚期GWG不足与不良妊娠结局之间无显著关联。总GWG不足的参与者早产风险显著较低（优势比[OR]，0.17；95%置信区间[CI]，0.05 - 0.60），高出生体重风险也显著较低（OR，0.23；95%CI，0.07 - 0.80）。
我们的研究结果表明了适当体重管理的重要性以及为患有GDM的孕妇制定GWG指南的必要性。
