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血液透析患者动静脉瘘管护理连续体中的种族差异。

Racial Disparities in the Arteriovenous Fistula Care Continuum in Hemodialysis Patients.

机构信息

Medical Technology and Practice Patterns Institute, Bethesda, Maryland.

Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.

出版信息

Clin J Am Soc Nephrol. 2020 Dec 7;15(12):1796-1803. doi: 10.2215/CJN.03600320. Epub 2020 Oct 20.

Abstract

BACKGROUND AND OBJECTIVES

Arteriovenous fistulas are the optimal vascular access type for patients on hemodialysis. However, arteriovenous fistulas are used less frequently in Black than in White individuals. The arteriovenous fistula care continuum comprises a series of sequential steps. A better understanding is needed of where disparities exist along the continuum in order to mitigate racial differences in arteriovenous fistula use.

DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Using Medicare claims data from the United States Renal Data System, longitudinal analyses of patients ≥67 years initiating hemodialysis with a central venous catheter between July 1, 2010 and June 30, 2012 were performed. Three patient cohorts were identified: patients initiating hemodialysis with a catheter (=41,814), patients with arteriovenous fistula placement within 6 months of dialysis initiation (=14,077), and patients whose arteriovenous fistulas were successfully used within 6 months of placement (=7068). Three arteriovenous fistula processes of care outcomes were compared between Blacks and Whites: () arteriovenous fistula creation, () successful arteriovenous fistula use, and () primary arteriovenous fistula patency after successful use.

RESULTS

An arteriovenous fistula was placed within 6 months of dialysis initiation in 37% of patients initiating dialysis with a catheter. Among the patients with arteriovenous fistula placement, the arteriovenous fistula was successfully used for dialysis within 6 months in 48% of patients. Among patients with successful arteriovenous fistula use, 21% maintained primary arteriovenous fistula patency at 3 years. After adjusting for competing risks, Black patients on hemodialysis were 10% less likely to undergo arteriovenous fistula placement (adjusted subdistribution hazard ratio, 0.90; 95% confidence interval, 0.87 to 0.94); 12% less likely to have successful arteriovenous fistula use after placement (adjusted subdistribution hazard ratio, 0.88; 95% confidence interval, 0.83 to 0.93); and 22% less likely to maintain primary arteriovenous fistula patency after successful use (subdistribution hazard ratio, 0.78; 95% confidence interval, 0.74 to 0.84).

CONCLUSIONS

Lower arteriovenous fistula use among Blacks older than 67 years of age treated with hemodialysis was attributable to each step along the continuum of arteriovenous fistula processes of care.

摘要

背景与目的

动静脉瘘是血液透析患者的最佳血管通路类型。然而,黑种人使用动静脉瘘的频率低于白种人。动静脉瘘护理连续体包括一系列连续的步骤。为了减轻动静脉瘘使用方面的种族差异,需要更好地了解连续体中存在差异的地方。

设计、设置、参与者和测量:使用来自美国肾脏数据系统的医疗保险索赔数据,对 2010 年 7 月 1 日至 2012 年 6 月 30 日期间开始血液透析并带有中央静脉导管的年龄≥67 岁的患者进行了纵向分析。确定了三个患者队列:开始血液透析时带有导管的患者(=41814)、在透析开始后 6 个月内放置动静脉瘘的患者(=14077)和在放置后 6 个月内成功使用动静脉瘘的患者(=7068)。在黑人和白人之间比较了三个动静脉瘘护理过程的结果:()动静脉瘘的建立,()成功使用动静脉瘘,以及()成功使用后的主要动静脉瘘通畅率。

结果

在开始透析时带有导管的患者中,有 37%在透析开始后 6 个月内放置了动静脉瘘。在放置动静脉瘘的患者中,有 48%的患者在 6 个月内成功将动静脉瘘用于透析。在成功使用动静脉瘘的患者中,有 21%的患者在 3 年内保持主要动静脉瘘通畅率。在调整了竞争风险后,血液透析的黑人患者进行动静脉瘘放置的可能性降低了 10%(调整后的亚分布危险比,0.90;95%置信区间,0.87 至 0.94);放置后成功使用动静脉瘘的可能性降低了 12%(调整后的亚分布危险比,0.88;95%置信区间,0.83 至 0.93);成功使用后保持主要动静脉瘘通畅率的可能性降低了 22%(亚分布危险比,0.78;95%置信区间,0.74 至 0.84)。

结论

年龄大于 67 岁接受血液透析治疗的黑人患者动静脉瘘使用率较低,这归因于动静脉瘘护理连续体中的每一个步骤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62a4/7769016/09b54685e730/CJN.03600320absf1.jpg

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